News and Views
Nature Neuroscience 12, 243 - 245 (2009)
doi:10.1038/nn0309-243
Notch keeps ependymal cells in line
Chunmei Zhao1, Hoonkyo Suh1 & Fred H Gage1
- The authors are at the Laboratory of Genetics, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037, USA. e-mail: gage@salk.edu
Abstract
The ependymal cells lining the lateral ventricles are not stem cells, but a study now shows that they can be activated to generate neuroblasts in a stroke model, and mature olfactory bulb neurons when Notch signaling is disrupted.
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