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Nature Neuroscience 12, 105 - 106 (2009)
doi:10.1038/nn0209-105

Whither proBDNF?

Philip A Barker1

  1. Philip A. Barker is at the Montreal Neurological Institute, McGill University, Montreal, Quebec H3A 2B4, Canada. e-mail: phil.barker@mcgill.ca


ProBDNF has been proposed to alter synaptic plasticity, but whether it is normally released from neurons has been a matter of contention. New work suggests that proBDNF is indeed secreted from central neurons.

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