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Brief Communication
Nature Neuroscience 12, 1485–1487 (1 December 2009) | doi:10.1038/nn.2428
Experience-dependent compartmentalized dendritic plasticity in rat hippocampal CA1 pyramidal neurons
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Abstract
The excitability of individual dendritic branches is a plastic property of neurons. We found that experience in an enriched environment increased propagation of dendritic Na+ spikes in a subset of individual dendritic branches in rat hippocampal CA1 pyramidal neurons and that this effect was mainly mediated by localized downregulation of A-type K+ channel function.
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