Cholinergic neurons in the basal forebrain enable alert and attending brain states. A study now shows how basal forebrain activity increases coding abilities of cortical neurons and at what stages these changes occur.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout
References
Metherate, R., Cox, C.L. & Ashe, J.H. J. Neurosci. 12, 4701–4711 (1992).
Buzsaki, G. et al. J. Neurosci. 8, 4007–4026 (1988).
Parikh, V., Kozak, R., Martinez, V. & Sarter, M. Neuron 56, 141–154 (2007).
Herrero, J.L. et al. Nature 454, 1110–1114 (2008).
Goard, M. & Dan, Y. Nat. Neurosci. 12, 1444–1449 (2009).
Hasselmo, M.E. & Bower, J.M. J. Neurophysiol. 67, 1222–1229 (1992).
Gil, Z., Connors, B.W. & Amitai, Y. Neuron 19, 679–686 (1997).
McAlonan, K., Cavanaugh, J. & Wurtz, R.H. Nature 456, 391–394 (2008).
Levey, A.I., Hallanger, A.E. & Wainer, B.H. Neurosci. Lett. 74, 7–13 (1987).
Sillito, A.M. & Kemp, J.A. Brain Res. 289, 143–155 (1983).
Zinke, W. et al. Eur. J. Neurosci. 24, 314–328 (2006).
Gregoriou, G.G., Gotts, S.J., Zhou, H. & Desimone, R. Science 324, 1207–1210 (2009).
Mitchell, J.F., Sundberg, K.A. & Reynolds, J.H. Neuron 55, 131–141 (2007).
Roelfsema, P.R., Lamme, V.A. & Spekreijse, H. Nat. Neurosci. 7, 982–991 (2004).
Mitchell, J.F., Sundberg, K.A. & Reynolds, J.H. Neuron 63, 879–888 (2009).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Thiele, A. Optimizing brain processing. Nat Neurosci 12, 1359–1360 (2009). https://doi.org/10.1038/nn1109-1359
Issue Date:
DOI: https://doi.org/10.1038/nn1109-1359
This article is cited by
-
An acetylcholine-activated microcircuit drives temporal dynamics of cortical activity
Nature Neuroscience (2015)