Brief Communication abstract


Nature Neuroscience 12, 1370 - 1371 (2009)
Published online: 11 October 2009 | doi:10.1038/nn.2412

Training induces changes in white-matter architecture

Jan Scholz1, Miriam C Klein1,2, Timothy E J Behrens1,2 & Heidi Johansen-Berg1

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Although experience-dependent structural changes have been found in adult gray matter, there is little evidence for such changes in white matter. Using diffusion imaging, we detected a localized increase in fractional anisotropy, a measure of microstructure, in white matter underlying the intraparietal sulcus following training of a complex visuo-motor skill. This provides, to the best of our knowledge, the first evidence for training-related changes in white-matter structure in the healthy human adult brain.

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  1. Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, Oxford, UK.
  2. Department of Experimental Psychology, University of Oxford, Oxford, UK.

Correspondence to: Jan Scholz1 e-mail: jscholz@fmrib.ox.ac.uk