Brief Communication abstract

Nature Neuroscience 12, 1370 - 1371 (2009)
Published online: 11 October 2009 | doi:10.1038/nn.2412

Training induces changes in white-matter architecture

Jan Scholz1, Miriam C Klein1,2, Timothy E J Behrens1,2 & Heidi Johansen-Berg1


Although experience-dependent structural changes have been found in adult gray matter, there is little evidence for such changes in white matter. Using diffusion imaging, we detected a localized increase in fractional anisotropy, a measure of microstructure, in white matter underlying the intraparietal sulcus following training of a complex visuo-motor skill. This provides, to the best of our knowledge, the first evidence for training-related changes in white-matter structure in the healthy human adult brain.

  1. Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, Oxford, UK.
  2. Department of Experimental Psychology, University of Oxford, Oxford, UK.

Correspondence to: Jan Scholz1 e-mail: