Brief Communication abstract
Nature Neuroscience 12, 32 - 34 (2008)
Published online: 23 November 2008 | doi:10.1038/nn.2228
Connectivity-based segregation of the human striatum predicts personality characteristics
Michael X Cohen1,2, Jan-Christoph Schoene-Bake1, Christian E Elger1 & Bernd Weber1
We found that personality characteristics are linked to dissociable connectivity streams in the human brain. Whereas fiber tracts between a subcortical network, including the hippocampus and amygdala, and the ventral striatum predicted individual differences in novelty seeking, tracts between prefrontal cortex and the striatum predicted individual differences in reward dependence. These findings suggest that the strength of limbic-striatal connectivity may, in part, underlie human personality traits.
- Department of Epileptology and Life & Brain Center, Department of NeuroCognition, University of Bonn, Sigmund Freud Street 25, Bonn 53105, Germany.
- Department of Psychology, University of Arizona, 1503 E University Boulevard, PO Box 210068, Psychology Bldg., Tucson, Arizona 85721, USA.
Correspondence to: Michael X Cohen1,2 e-mail: mikexcohen@gmail.com
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