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Nature Neuroscience 11, 857–859 (1 August 2008) | doi:10.1038/nn0808-857

Unraveling the ribbon synapse

Jakob S Satz & Kevin P Campbell

Synaptogenesis requires the precise targeting of axons, the apposition of presynaptic and postsynaptic termini, as well as the proper differentiation and maturation of synaptic termini. In retinal photoreceptor ribbon synapses, bipolar cells and horizontal cells contact rod or cone photoreceptors through invaginations of the photoreceptor termini.