News and Views


Nature Neuroscience 11, 857 - 859 (2008)
doi:10.1038/nn0808-857

Unraveling the ribbon synapse

Jakob S Satz1 & Kevin P Campbell2

  1. The authors are at the Howard Hughes Medical Institute, Department of Molecular Physiology and Biophysics, 4283 Carver Biomedical Research Building, 285 Newton Road, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA.
  2. Kevin P Campbell is also a member of the Departments of Neurology and Internal Medicine, 4283 Carver Biomedical Research Building, 285 Newton Road, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA.
    e-mail: kevin-campbell@uiowa.edu


A new study identifies pikachurin, a previously-unknown dystroglycan-binding protein that is critical for the apposition of photoreceptor and bipolar cell dendrites at the ribbon synapse. This work could explain some of the visual defects seen in several muscular dystrophies.

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