Brief Communication abstract


Nature Neuroscience 11, 874 - 876 (2008)
Published online: 20 July 2008 | doi:10.1038/nn.2161

Suppression of male courtship by a Drosophila pheromone receptor

Tetsuya Miyamoto1 & Hubert Amrein1

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In male Drosophila, chemosensory cues control many aspects of social behavior. We found that males with a mutated Gustatory receptor 32a gene (Gr32a) show high courtship toward males and mated females, indicating that GR32a functions as a pheromone receptor for a male inhibitory pheromone. Notably, we discovered that tarsal Gr32a-expressing neurons were essential for courtship suppression and projected to the ventrolateral protocerebrum, implying direct communication of chemosensory neurons with a higher-order brain structure.

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  1. Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina 27710, USA.

Correspondence to: Hubert Amrein1 e-mail: hoa1@duke.edu



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