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Brief Communication
Nature Neuroscience 11, 637–639 (1 June 2008) | doi:10.1038/nn.2121
Thinning of sensorimotor cortices in children with Tourette syndrome
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Abstract
The basal ganglia portions of cortico-striato-thalamo-cortical (CSTC) circuits have consistently been implicated in the pathogenesis of Tourette syndrome, whereas motor and sensorimotor cortices in these circuits have been relatively overlooked. Using magnetic resonance imaging, we detected cortical thinning in frontal and parietal lobes in groups of Tourette syndrome children relative to controls.
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