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Focus on Decision Making

The ability to make appropriate choices is critical for survival. Successful decision making requires the integration of sensory information, motivational states and potential outcomes to select the best action. Recently, there has been great progress in our understanding of the neural mechanisms supporting decision making in a wide range of contexts, including risky choices and social interactions. This special focus on decision making contains four reviews that highlight recent achievements in this important field.

Editorial

Reducing the costs of peer review p375

doi:10.1038/nn0408-375


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Book Review

Exploring music's links to language p377

Josh H McDermott reviews Music, Language, and the Brain by Aniruddh D Patel

doi:10.1038/nn0408-377


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News and Views

Glia get excited pp379 - 380

Thomas S Otis & Michael V Sofroniew

doi:10.1038/nn0408-379

See also: Article by Káradóttir et al.


NMDA receptor activity regulates transcription of antioxidant pathways pp381 - 382

Stuart A Lipton

doi:10.1038/nn0408-381

See also: Article by Papadia et al.


Language evolution: neural differences that make a difference pp382 - 384

Asif A Ghazanfar

doi:10.1038/nn0408-382

See also: Brief Communication by Rilling et al.


What's in your mind? pp384 - 385

Brian A Wandell

doi:10.1038/nn0408-384


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Introduction

Focus on decision making p387

Hannah Bayer

doi:10.1038/nn0408-387


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Reviews

Choice, uncertainty and value in prefrontal and cingulate cortex pp389 - 397

Matthew F S Rushworth & Timothy E J Behrens

doi:10.1038/nn2066


Risky business: the neuroeconomics of decision making under uncertainty pp398 - 403

Michael L Platt & Scott A Huettel

doi:10.1038/nn2062


Game theory and neural basis of social decision making pp404 - 409

Daeyeol Lee

doi:10.1038/nn2065


Modulators of decision making pp410 - 416

Kenji Doya

doi:10.1038/nn2077


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Brief Communications

Redefining the serotonergic system by genetic lineage pp417 - 419

Patricia Jensen, Anna F Farago, Rajeshwar B Awatramani, Michael M Scott, Evan S Deneris & Susan M Dymecki

doi:10.1038/nn2050


ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration pp420 - 422

Zhihui Zhong, Rashid Deane, Zarina Ali, Margaret Parisi, Yuriy Shapovalov, M Kerry O'Banion, Konstantin Stojanovic, Abhay Sagare, Severine Boillee, Don W Cleveland & Berislav V Zlokovic

doi:10.1038/nn2073


Emotional environments retune the valence of appetitive versus fearful functions in nucleus accumbens pp423 - 425

Sheila M Reynolds & Kent C Berridge

doi:10.1038/nn2061


The evolution of the arcuate fasciculus revealed with comparative DTI pp426 - 428

James K Rilling, Matthew F Glasser, Todd M Preuss, Xiangyang Ma, Tiejun Zhao, Xiaoping Hu & Timothy E J Behrens

doi:10.1038/nn2072

See also: News and Views by Ghazanfar


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Articles

Compartment-specific transcription factors orchestrate angiogenesis gradients in the embryonic brain pp429 - 439

Anju Vasudevan, Jason E Long, James E Crandall, John L R Rubenstein & Pradeep G Bhide

doi:10.1038/nn2074


Plexin-A2 and its ligand, Sema6A, control nucleus-centrosome coupling in migrating granule cells pp440 - 449

Julie Renaud, Géraldine Kerjan, Itsuko Sumita, Yvrick Zagar, Virginie Georget, Doyeun Kim, Coralie Fouquet, Kazunori Suda, Makoto Sanbo, Fumikazu Suto, Susan L Ackerman, Kevin J Mitchell, Hajime Fujisawa & Alain Chédotal

doi:10.1038/nn2064


Spiking and nonspiking classes of oligodendrocyte precursor glia in CNS white matter pp450 - 456

Ragnhildur Káradóttir, Nicola B Hamilton, Yamina Bakiri & David Attwell

doi:10.1038/nn2060

See also: News and Views by Otis & Sofroniew


Motor protein–dependent transport of AMPA receptors into spines during long-term potentiation pp457 - 466

Susana S Correia, Silvia Bassani, Tyler C Brown, Marie-France Lisé, Donald S Backos, Alaa El-Husseini, Maria Passafaro & José A Esteban

doi:10.1038/nn2063


Development and spike timing–dependent plasticity of recurrent excitation in the Xenopus optic tectum pp467 - 475

Kara G Pratt, Wei Dong & Carlos D Aizenman

doi:10.1038/nn2076


Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses pp476 - 487

Sofia Papadia, Francesc X Soriano, Frédéric Léveillé, Marc-Andre Martel, Kelly A Dakin, Henrik H Hansen, Angela Kaindl, Marco Sifringer, Jill Fowler, Vanya Stefovska, Grahame Mckenzie, Marie Craigon, Roderick Corriveau, Peter Ghazal, Karen Horsburgh, Bruce A Yankner, David J A Wyllie, Chrysanthy Ikonomidou & Giles E Hardingham

doi:10.1038/nn2071

See also: News and Views by Lipton


Persistent restoration of sensory function by immediate or delayed systemic artemin after dorsal root injury pp488 - 496

Ruizhong Wang, Tamara King, Michael H Ossipov, Anthony J Rossomando, Todd W Vanderah, Pamela Harvey, Peter Cariani, Eric Frank, Dinah W Y Sah & Frank Porreca

doi:10.1038/nn2069


TrkB kinase is required for recovery, but not loss, of cortical responses following monocular deprivation pp497 - 504

Megumi Kaneko, Jessica L Hanover, Pamela M England & Michael P Stryker

doi:10.1038/nn2068



Smokers' brains compute, but ignore, a fictive error signal in a sequential investment task pp514 - 520

Pearl H Chiu, Terry M Lohrenz & P Read Montague

doi:10.1038/nn2067


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