1. The authors are at the Department of Neurobiology, Geffen School of Medicine at the University of California, Los Angeles, 10833 Le Conte Avenue, Los Angeles, California 90095. e-mail: otist@ucla.edu or e-mail: sofroniew@mednet.ucla.edu

Abstract

A new study shows that a subset of the glia that express the proteoglycan NG2 can fire action potentials, contradicting the dogma that only neurons are excitable in the brain. These glia receive excitatory and inhibitory synaptic input, are selectively vulnerable to ischemia and are present into adulthood, though their function remains mysterious.

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