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Nature Neuroscience 11, 243 - 244 (2008)
doi:10.1038/nn0308-243

Calcium: first messenger

Nicholas C Spitzer1

  1. The author is in the Neurobiology Section, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093-0357, USA. e-mail: nspitzer@ucsd.edu


Calcium is a ubiquitous second messenger in the nervous system linking extracellular and intracellular events. Now a study identifies it as a primary messenger controlling axon and dendrite outgrowth during development via activation of extracellular calcium-sensing receptors, better known in the liver and thyroid than in the brain.

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