News and Views


Nature Neuroscience 11, 124 - 126 (2008)
doi:10.1038/nn0208-124

Why endocannabinoids are not all alike

Vincenzo Di Marzo1 & Luigia Cristino1

  1. Vincenzo Di Marzo is at the Endocannabinoid Research Group, Istituto di Chimica Biomolecolare and Luigia Cristino is at the Istituto di Cibernetica, Consiglio Nazionale delle Ricerche, Via Campi Flegrei 34, Comprensorio Olivetti, 80078, Pozzuoli (NA), Italy. e-mail: vdimarzo@icmib.na.cnr.it


New work in this issue shows that one principal endocannabinoid, anandamide, directly inhibits the synthesis of another, 2-arachidonoylglycerol. This finding could explain a number of puzzling observations in the endocannabinoid field.

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