News and Views


Nature Neuroscience 11, 1365 - 1367 (2008)
Corrected online: 16 December 2008 | doi:10.1038/nn1208-1365

Glial progenitor cells in the adult brain reveal their alternate fate

Shin H Kang1 & Dwight E Bergles1

  1. The authors are at the Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 725 N. Wolfe Street, WBSB 1001, Baltimore, Maryland 21205, USA. e-mail: dbergles@jhmi.edu


Glial cells that express NG2 and platelet-derived growth factor receptor alpha are found throughout the mature CNS. These cells are mitotically active, but their functions remain enigmatic. A genetic fate-mapping study in this issue shows that these abundant glial cells can generate both oligodendrocytes and some cortical projection neurons in the adult brain.

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* In the version of this article initially published, in Figure 1c, mature oligodendrocytes are incorrectly labeled as 'NeuN+'. This should be 'NeuN–'. The error has been corrected in the HTML and PDF versions of the article.

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Glial progenitor cells in the adult brain reveal their alternate fate

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