Oldham et al. present a systematic analysis of gene coexpression relationships in specific human brain regions with the goal of identifying groups of genes with common coexpression patterns. The study used the inherent structure of the brain's transcriptome to find data-driven organizational patterns rather than rely on external classification systems.
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Mirnics, K. What is in the brain soup?. Nat Neurosci 11, 1237–1238 (2008). https://doi.org/10.1038/nn1108-1237
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DOI: https://doi.org/10.1038/nn1108-1237