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Nature Neuroscience 11, 1126–1127 (1 October 2008) | doi:10.1038/nn1008-1126

Pavlov's moth: olfactory learning and spike timing|[ndash]|dependent plasticity

Julian P Meeks & Timothy E Holy

Pavlov and many others have noticed that timing is important in learning; for example, any action (such as ringing a bell) that typically precedes feeding tends to be quickly associated with an impending meal. Neuroscientists have long sought the circuit and cellular mechanisms that underlie such learning.