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Brief Communication

Nature Neuroscience 11, 16–18 (1 January 2008) | doi:10.1038/nn2016

Recognition memory: opposite effects of hippocampal damage on recollection and familiarity

Magdalena M Sauvage , Norbert J Fortin , Cullen B Owens , Andrew P Yonelinas & Howard Eichenbaum

A major controversy in memory research concerns whether recognition is subdivided into distinct cognitive mechanisms of recollection and familiarity that are supported by different neural substrates. Here we developed a new associative recognition protocol for rats that enabled us to show that recollection is reduced, whereas familiarity is increased following hippocampal damage.