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Brief Communication
Nature Neuroscience 10, 1128–1130 (1 September 2007) | doi:10.1038/nn1952
Cell type|[ndash]|specific gating of perisomatic inhibition by cholecystokinin
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Abstract
Parvalbumin- and cholecystokinin (CCK)-expressing basket cells provide two parallel, functionally distinct sources of perisomatic inhibition to postsynaptic cells. We show that exogenously applied CCK enhances the output from rat parvalbumin-expressing basket cells, while concurrently suppressing GABA release from CCK-expressing neurons through retrograde endocannabinoid action.
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