Brief Communication abstract
Nature Neuroscience 10, 1137 - 1139 (2007)
Published online: 29 July 2007 | doi:10.1038/nn1945
A deletion variant of the
2b-adrenoceptor is related to emotional memory in Europeans and Africans
Dominique J-F de Quervain1,2, Iris-Tatjana Kolassa3, Verena Ertl3, P Lamaro Onyut3,4, Frank Neuner3, Thomas Elbert3 & Andreas Papassotiropoulos5,6
Emotionally arousing events are recalled better than neutral events. This phenomenon, which helps us to remember important and potentially vital information, depends on the activation of noradrenergic transmission in the brain. Here we show that a deletion variant of ADRA2B, the gene encoding the
2b-adrenergic receptor, is related to enhanced emotional memory in healthy Swiss subjects and in survivors of the Rwandan civil war who experienced highly aversive emotional situations.
- Division of Psychiatry Research, University of Zürich, Lenggstr. 31, 8032 Zürich, Switzerland.
- Center for Integrative Human Physiology, University of Zürich, 8057, Zürich, Switzerland.
- Department of Psychology, University of Konstanz, D25, 78457 Konstanz, Germany.
- Faculty of Science and Education, Mbarara University of Science & Technology, P.O. Box 1410, Mbarara, Uganda.
- Division of Molecular Psychology, University of Basel, Missionsstr. 62a, 4055 Basel, Switzerland.
- Life Sciences Training Facility, Biozentrum, University of Basel, Klingelbergstr. 50/70, 4056 Basel, Switzerland.
Correspondence to: Dominique J-F de Quervain1,2 e-mail: quervain@bli.unizh.ch
Correspondence to: Andreas Papassotiropoulos5,6 e-mail: andreas.papas@unibas.ch
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A deletion variant of the α2b-adrenoceptor is related to emotional memory in Europeans and AfricansNature Neuroscience Brief Communication (01 Sep 2007)

