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Nature Neuroscience 10, 1079 - 1080 (2007)
doi:10.1038/nn0907-1079

Soporific signaling: how flies sleep through the night

Christopher S Colwell1

  1. Christopher S. Colwell is in the Department of Psychiatry and Biobehavioral Sciences, Laboratory of Circadian Neurobiology, University of California Los Angeles, 760 Westwood Plaza, Los Angeles, California 90024-1759, USA. e-mail: ccolwell@mednet.ucla.edu


The mechanisms of sleep have been studied in Drosophila melanogaster, which show behaviors reminiscent of sleep in vertebrates. A new study identifies a growth factor signaling pathway involved in sleep regulation and consolidation in this model. Inhibiting this pathway causes a sleep pattern that is similar to insomnia in humans.

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