Article abstract


Nature Neuroscience 10, 772 - 778 (2007)
Published online: 29 April 2007 | doi:10.1038/nn1895

Rapid learning in cortical coding of visual scenes

Haishan Yao1,2, Lei Shi2, Feng Han3, Hongfeng Gao1,2 & Yang Dan1,2,3


Experience-dependent plasticity in adult visual cortex is believed to have important roles in visual coding and perceptual learning. Here we show that repeated stimulation with movies of natural scenes induces a rapid improvement in response reliability in cat visual cortex, whereas stimulation with white noise or flashed bar stimuli does not. The improved reliability can be accounted for by a selective increase in spiking evoked by preferred stimuli, and the magnitude of improvement depends on the sparseness of the response. The increase in reliability persists for at least several minutes in the absence of further movie stimulation. During this period, spontaneous spiking activity shows detectable reverberation of the movie-evoked responses. Thus, repeated exposure to natural stimuli not only induces a rapid improvement in cortical response reliability, but also leaves a 'memory trace' in subsequent spontaneous activity.

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  1. Division of Neurobiology, Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA.
  2. Helen Wills Neuroscience Institute, University of California at Berkeley, Berkeley, California 94720, USA.
  3. Group in Vision Science, University of California at Berkeley, Berkeley, California 94720, USA.

Correspondence to: Yang Dan1,2,3 e-mail: ydan@berkeley.edu

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