News and Views


Nature Neuroscience 10, 675 - 677 (2007)
doi:10.1038/nn0607-675

Pure spillover transmission between neurons

Hiroshi Nishiyama1 & David J Linden1

  1. The authors are at the Department of Neuroscience, The Johns Hopkins University School of Medicine, 725 N. Wolfe Street, Baltimore, Maryland 21205, USA. e-mail: dlinden@jhmi.edu


Szapiro and Barbour describe a new mode of neuron-to-neuron communication mediated solely by spillover of neurotransmitter that diffuses out of the synaptic cleft to bind more distant receptors on postsynaptic neurons.

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