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Nature Neuroscience 10, 537 - 538 (2007)
doi:10.1038/nn0507-537
Something old, something new: BDNF-induced neuron survival requires TRPC channel function
Wayne S Sossin1 & Philip A Barker1
- Wayne Sossin and Phil Barker are at the Montreal Neurological Institute, McGill University, 3801 University Avenue, Montreal, Quebec H3A2B4, Canada. e-mail: wayne.sossin@mcgill.ca or e-mail: phil.barker@mcgill.ca
Abstract
Transient receptor potential (TRP) channels participate in many diverse neuronal functions. A study in this issue now shows that TRPC-dependent calcium fluxes are also crucial to neurotrophin-induced cell survival signaling.
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Tyrosine phosphatase SHP-2 is a mediator of activity-dependent neuronal excitotoxicityThe EMBO Journal Article (26 Jan 2005)
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