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Nature Neuroscience 10, 399 - 400 (2007)
doi:10.1038/nn0407-399
Synapses go nucle(ol)ar
Joel D Richter1 & Justin R Fallon1
- Joel D. Richter is at the Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation St., Suite 204, Worcester, Massachusetts 01605, USA.
- Justin R. Fallon is at the Department of Neuroscience, Brown University, Box G-L, Sidney Frank Hall 358, 185 Meeting St., Providence, Rhode Island 02912, USA. e-mail: justin_fallon@brown.edu
Abstract
Jordan and colleagues report that activity causes the shuttling of a synaptic protein AIDA-1d from dendritic spines to the nucleus. This work sheds light on how nuclear protein synthesis is regulated in response to synaptic activity.
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RESEARCH
Activity-dependent AIDA-1 nuclear signaling regulates nucleolar numbers and protein synthesis in neuronsNature Neuroscience Article (01 Apr 2007)
