Access

Brief Communication

Nature Neuroscience 10, 1513–1514 (1 December 2007) | doi:10.1038/nn2010

Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA

Matthew E Klein , Daniel T Lioy , Lin Ma , Soren Impey , Gail Mandel & Richard H Goodman

Both increases and decreases in methyl CpG–binding protein 2 (MeCP2) levels cause neurodevelopmental defects. We found that MeCP2 translation is regulated by microRNA 132 (miR132).