Table of contents
November 2007, Volume 10 No 11 pp1337-1499
About the coverFocus
Focus on Glia and Disease
- Focus issue:
- November 2007 Volume 10, No 11
Glia are critical to many brain disorders. Glial cells regulate brain vasculature and the blood-brain barrier, modulating ischemia and blood flow changes in response to neural activity. Moreover, they are important in brain repair after injury and contribute to neurodegenerative diseases. This special focus on glia and disease contains four reviews and two perspectives that highlight recent research in these areas and discuss how advances in understanding glial biology may lead to new treatments.
Editorial
Supply-side academics - p1337
doi:10.1038/nn1107-1337
Full Text - Supply-side academics | PDF (111 KB) - Supply-side academics
Book Review
The most wonderful organ—not! - p1339
Charles Jennings reviews The Accidental Mind by David J. Linden
doi:10.1038/nn1107-1339
Full Text - The most wonderful organ—not! | PDF (73 KB) - The most wonderful organ—not!
News and Views
Glycogen: a Trojan horse for neurons - pp1341 - 1342
Pierre J Magistretti & Igor Allaman
doi:10.1038/nn1107-1341
Full Text - Glycogen: a Trojan horse for neurons | PDF (186 KB) - Glycogen: a Trojan horse for neurons
See also: Article by Vilchez et al.
A step toward optimal coding in olfaction - pp1342 - 1343
L F Abbott & Sean X Luo
doi:10.1038/nn1107-1342
Full Text - A step toward optimal coding in olfaction | PDF (184 KB) - A step toward optimal coding in olfaction
See also: Article by Bhandawat et al.
Out of the spotlight: face to face with attention - pp1344 - 1345
Sabine Kastner & Stephanie A McMains
doi:10.1038/nn1107-1344
Full Text - Out of the spotlight: face to face with attention | PDF (98 KB) - Out of the spotlight: face to face with attention
See also: Article by Qiu et al.
The optimistic brain - pp1345 - 1347
Daniel L Schacter & Donna Rose Addis
doi:10.1038/nn1107-1345
Full Text - The optimistic brain | PDF (328 KB) - The optimistic brain
Olfactory axons derailed in the brain - p1347
Annette Markus
doi:10.1038/nn1107-1347
Full Text - Olfactory axons derailed in the brain | PDF (177 KB) - Olfactory axons derailed in the brain
See also: Article by Yao et al.
Introduction
Focus on Glia and Disease
Focus on glia and disease - p1349
Sandra Aamodt
doi:10.1038/nn1107-1349
Full Text - Focus on glia and disease | PDF (116 KB) - Focus on glia and disease
Perspectives
Focus on Glia and Disease
Dissecting demyelination - pp1351 - 1354
Robert H Miller & Sha Mi
doi:10.1038/nn1995
Abstract - Dissecting demyelination | Full Text - Dissecting demyelination | PDF (248 KB) - Dissecting demyelination
Focus on Glia and Disease
Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease - pp1355 - 1360
Christian S Lobsiger & Don W Cleveland
doi:10.1038/nn1988
Abstract - Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease | Full Text - Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease | PDF (561 KB) - Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease
Reviews
Focus on Glia and Disease
The neuropathic pain triad: neurons, immune cells and glia - pp1361 - 1368
Joachim Scholz & Clifford J Woolf
doi:10.1038/nn1992
Abstract - The neuropathic pain triad: neurons, immune cells and glia | Full Text - The neuropathic pain triad: neurons, immune cells and glia | PDF (413 KB) - The neuropathic pain triad: neurons, immune cells and glia
Focus on Glia and Disease
Glial regulation of the cerebral microvasculature - pp1369 - 1376
Costantino Iadecola & Maiken Nedergaard
doi:10.1038/nn2003
Abstract - Glial regulation of the cerebral microvasculature | Full Text - Glial regulation of the cerebral microvasculature | PDF (581 KB) - Glial regulation of the cerebral microvasculature
Focus on Glia and Disease
Astrocyte metabolism and signaling during brain ischemia - pp1377 - 1386
David J Rossi, James D Brady & Claudia Mohr
doi:10.1038/nn2004
Abstract - Astrocyte metabolism and signaling during brain ischemia | Full Text - Astrocyte metabolism and signaling during brain ischemia | PDF (1,377 KB) - Astrocyte metabolism and signaling during brain ischemia
Focus on Glia and Disease
Microglia: active sensor and versatile effector cells in the normal and pathologic brain - pp1387 - 1394
Uwe-Karsten Hanisch & Helmut Kettenmann
doi:10.1038/nn1997
Abstract - Microglia: active sensor and versatile effector cells in the normal and pathologic brain | Full Text - Microglia: active sensor and versatile effector cells in the normal and pathologic brain | Supplementary information
Brief Communications
Genetic control of instrumental conditioning by striatopallidal neuron–specific S1P receptor Gpr6 - pp1395 - 1397
Mary Kay Lobo, Yijun Cui, Sean B Ostlund, Bernard W Balleine & X William Yang
doi:10.1038/nn1987
Abstract - Genetic control of instrumental conditioning by striatopallidal neuron-specific S1P receptor Gpr6 | Full Text - Genetic control of instrumental conditioning by striatopallidal neuron–specific S1P receptor Gpr6 | PDF (218 KB) - Genetic control of instrumental conditioning by striatopallidal neuron–specific S1P receptor Gpr6 | Supplementary information
Sex chromosome complement regulates habit formation - pp1398 - 1400
Jennifer J Quinn, Paul K Hitchcott, Elizabeth A Umeda, Arthur P Arnold & Jane R Taylor
doi:10.1038/nn1994
Abstract - Sex chromosome complement regulates habit formation | Full Text - Sex chromosome complement regulates habit formation | PDF (179 KB) - Sex chromosome complement regulates habit formation | Supplementary information
The hippocampus is necessary for enhancements and impairments of learning following stress - pp1401 - 1403
Debra A Bangasser & Tracey J Shors
doi:10.1038/nn1973
Abstract - The hippocampus is necessary for enhancements and impairments of learning following stress | Full Text - The hippocampus is necessary for enhancements and impairments of learning following stress | PDF (204 KB) - The hippocampus is necessary for enhancements and impairments of learning following stress | Supplementary information
A temporal frequency–dependent functional architecture in human V1 revealed by high-resolution fMRI - pp1404 - 1406
Pei Sun, Kenichi Ueno, R Allen Waggoner, Justin L Gardner, Keiji Tanaka & Kang Cheng
doi:10.1038/nn1983
Abstract - A temporal frequency-dependent functional architecture in human V1 revealed by high-resolution fMRI | Full Text - A temporal frequency–dependent functional architecture in human V1 revealed by high-resolution fMRI | PDF (277 KB) - A temporal frequency–dependent functional architecture in human V1 revealed by high-resolution fMRI | Supplementary information
Articles
Mechanism suppressing glycogen synthesis in neurons and its demise in progressive myoclonus epilepsy - pp1407 - 1413
David Vilchez, Susana Ros, Daniel Cifuentes, Lluís Pujadas, Jordi Vallès, Belén García-Fojeda, Olga Criado-García, Elena Fernández-Sánchez, Iria Medraño-Fernández, Jorge Domínguez, Mar García-Rocha, Eduardo Soriano, Santiago Rodríguez de Córdoba & Joan J Guinovart
doi:10.1038/nn1998
Abstract - Mechanism suppressing glycogen synthesis in neurons and its demise in progressive myoclonus epilepsy | Full Text - Mechanism suppressing glycogen synthesis in neurons and its demise in progressive myoclonus epilepsy | PDF (356 KB) - Mechanism suppressing glycogen synthesis in neurons and its demise in progressive myoclonus epilepsy | Supplementary information
See also: News and Views by Magistretti & Allaman
Neurological defects in trichothiodystrophy reveal a coactivator function of TFIIH - pp1414 - 1422
Emmanuel Compe, Monica Malerba, Luc Soler, Jacques Marescaux, Emiliana Borrelli & Jean-Marc Egly
doi:10.1038/nn1990
Abstract - Neurological defects in trichothiodystrophy reveal a coactivator function of TFIIH | Full Text - Neurological defects in trichothiodystrophy reveal a coactivator function of TFIIH | PDF (734 KB) - Neurological defects in trichothiodystrophy reveal a coactivator function of TFIIH | Supplementary information
Antagonistic roles of Wnt5 and the Drl receptor in patterning the Drosophila antennal lobe - pp1423 - 1432
Ying Yao, Yuping Wu, Chong Yin, Rie Ozawa, Toshiro Aigaki, Rene R Wouda, Jasprina N Noordermeer, Lee G Fradkin & Huey Hing
doi:10.1038/nn1993
Abstract - Antagonistic roles of Wnt5 and the Drl receptor in patterning the : Drosophila: antennal lobe | Full Text - Antagonistic roles of Wnt5 and the Drl receptor in patterning the Drosophila antennal lobe | PDF (1,936 KB) - Antagonistic roles of Wnt5 and the Drl receptor in patterning the Drosophila antennal lobe | Supplementary information
See also: News and Views by Markus
Transcriptional repression coordinates the temporal switch from motor to serotonergic neurogenesis - pp1433 - 1439
John Jacob, Anna L Ferri, Christopher Milton, Fabrice Prin, Patrick Pla, Wei Lin, Anthony Gavalas, Siew-Lan Ang & James Briscoe
doi:10.1038/nn1985
Abstract - Transcriptional repression coordinates the temporal switch from motor to serotonergic neurogenesis | Full Text - Transcriptional repression coordinates the temporal switch from motor to serotonergic neurogenesis | PDF (793 KB) - Transcriptional repression coordinates the temporal switch from motor to serotonergic neurogenesis | Supplementary information
Control of planar divisions by the G-protein regulator LGN maintains progenitors in the chick neuroepithelium - pp1440 - 1448
Xavier Morin, Florence Jaouen & Pascale Durbec
doi:10.1038/nn1984
Abstract - Control of planar divisions by the G-protein regulator LGN maintains progenitors in the chick neuroepithelium | Full Text - Control of planar divisions by the G-protein regulator LGN maintains progenitors in the chick neuroepithelium | PDF (978 KB) - Control of planar divisions by the G-protein regulator LGN maintains progenitors in the chick neuroepithelium | Supplementary information
Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury - pp1449 - 1457
Pernille Jansen, Klaus Giehl, Jens R Nyengaard, Kenneth Teng, Oleg Lioubinski, Susanne S Sjoegaard, Tilman Breiderhoff, Michael Gotthardt, Fuyu Lin, Andreas Eilers, Claus M Petersen, Gary R Lewin, Barbara L Hempstead, Thomas E Willnow & Anders Nykjaer
doi:10.1038/nn2000
Abstract - Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury | Full Text - Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury | PDF (743 KB) - Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury | Supplementary information
Cholinergic modulation of Kir2 channels selectively elevates dendritic excitability in striatopallidal neurons - pp1458 - 1466
Weixing Shen, Xinyong Tian, Michelle Day, Sasha Ulrich, Tatiana Tkatch, Neil M Nathanson & D James Surmeier
doi:10.1038/nn1972
Abstract - Cholinergic modulation of Kir2 channels selectively elevates dendritic excitability in striatopallidal neurons | Full Text - Cholinergic modulation of Kir2 channels selectively elevates dendritic excitability in striatopallidal neurons | PDF (760 KB) - Cholinergic modulation of Kir2 channels selectively elevates dendritic excitability in striatopallidal neurons | Supplementary information
Sodium pumps adapt spike bursting to stimulus statistics - pp1467 - 1473
Sara Arganda, Raúl Guantes & Gonzalo G de Polavieja
doi:10.1038/nn1982
Abstract - Sodium pumps adapt spike bursting to stimulus statistics | Full Text - Sodium pumps adapt spike bursting to stimulus statistics | PDF (1,992 KB) - Sodium pumps adapt spike bursting to stimulus statistics | Supplementary information
Sensory processing in the Drosophila antennal lobe increases reliability and separability of ensemble odor representations - pp1474 - 1482
Vikas Bhandawat, Shawn R Olsen, Nathan W Gouwens, Michelle L Schlief & Rachel I Wilson
doi:10.1038/nn1976
Abstract - Sensory processing in the : Drosophila: antennal lobe increases reliability and separability of ensemble odor representations | Full Text - Sensory processing in the Drosophila antennal lobe increases reliability and separability of ensemble odor representations | PDF (378 KB) - Sensory processing in the Drosophila antennal lobe increases reliability and separability of ensemble odor representations | Supplementary information
See also: News and Views by Abbott & Luo
Attention alters spatial integration in macaque V1 in an eccentricity-dependent manner - pp1483 - 1491
Mark Roberts, Louise S Delicato, Jose Herrero, Mark A Gieselmann & Alexander Thiele
doi:10.1038/nn1967
Abstract - Attention alters spatial integration in macaque V1 in an eccentricity-dependent manner | Full Text - Attention alters spatial integration in macaque V1 in an eccentricity-dependent manner | PDF (402 KB) - Attention alters spatial integration in macaque V1 in an eccentricity-dependent manner | Supplementary information
Figure-ground mechanisms provide structure for selective attention - pp1492 - 1499
Fangtu T Qiu, Tadashi Sugihara & Rüdiger von der Heydt
doi:10.1038/nn1989
Abstract - Figure-ground mechanisms provide structure for selective attention | Full Text - Figure-ground mechanisms provide structure for selective attention | PDF (486 KB) - Figure-ground mechanisms provide structure for selective attention | Supplementary information
See also: News and Views by Kastner & McMains
