Figure 3 : Astrocyte metabolism and signaling during brain ischemia : Nature Neuroscience

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Astrocyte metabolism and signaling during brain ischemia

David J Rossi, James D Brady & Claudia Mohr

Nature Neuroscience 10, 1377 - 1386 (2007) Published online: 26 October 2007

doi:10.1038/nn2004

Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

AdR, adenosine receptor; AMPAR, AMPA receptor; AQP, aquaporin channel; ASIC, acid-sensing ion channels; GSH, glutathione; HC, connexin hemichannel; mGluR, metabotropic glutamate receptor; mito. Ca²⁺, mitochondrial calcium; NR2A/B, NMDA receptor with subunit 2A or B, respectively; P2XR, P2X receptor; V-gate, voltage-gated calcium channel; ^*ion flux through various unidentified ion channels. Details of evidence and our speculations in the text.

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Figure 3 - Summary diagram of the processes in neurons and astrocytes which have been shown to or could in principle contribute to the rise in [Glu]o and [Ca2+]i.

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Figure 3 - Summary diagram of the processes in neurons and astrocytes which have been shown to or could in principle contribute to the rise in [Glu]_o and [Ca²⁺]_i.