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November 2007 Volume 10 No 11

Glial cells contribute significantly to neuronal health and disease. Glia are implicated in the regulation of brain vasculature (and therefore ischemia and stroke) as well as myelination and repair, suggesting a role in neurodegenerative diseases. In this issue, we present six reviews and perspectives on the importance of glia in disease. The cover shows astrocytes in human parietal cortex, identified by GFAP labeling, courtesy of NancyAnn Oberheim and Takahiro Takano. (pp 1349-1394)

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