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Cortico-hippocampal interaction during up-down states and memory consolidation

Sleep may promote the transfer of memories from hippocampus to cortex. New work shows that experiences are replayed during sleep in both brain regions and that replay in these two areas occurs synchronously.

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Figure 1: Interaction between inputs and synaptic matrix in governing sleep replay.

Kimberly Caesar

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Mehta, M. Cortico-hippocampal interaction during up-down states and memory consolidation. Nat Neurosci 10, 13–15 (2007). https://doi.org/10.1038/nn0107-13

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