Axon guidance mechanisms: semaphorins as simultaneous repellents and
anti-repellents
Hang Chen, Zhigang He
& Marc Tessier-Lavigne
Hang Chen, Zhigang He and Marc Tessier-Lavigne are at the
Departments of Anatomy of Biochemistry and Biophysics, Howard Hughes Medical
Institute, University of California, San Francisco,
California 94143-0452, USA marctl@itsa.ucsf.edu
Semaphorins A and E are known to potently repel sympathetic axons. New
work indicates that they can also antagonize the repellent action of semaphorin
D at sensory axons.