Ion-binding sites in NMDA receptors: classical approaches provide the
numbers
Mark Mayer
Laboratory of Cellular and Molecular Neurophysiology,
NICHD, NIH, Building 49, Room 5A78, Bethesda, Maryland 20892, USA MLM@HELIX.NIH.GOV
The structure of glutamate receptor pores is not well defined. A new study
reveals multiple Na+ binding sites in NMDA receptors, occupancy
of which interferes with channel blockers.
