Table of contents
August 2008 Volume 5 No 8
Research Highlights
Increase in detection of early RCC might improve survival
410Vitamin D concentration does not affect the risk of prostate cancer
410Erectile dysfunction predicts coronary heart disease in patients with type 2 diabetes
410Men with breast cancer have an increased incidence of prostate cancer
411Organochlorine pesticides increase risk of germ cell cancers
411Erectile dysfunction is associated with thyroid dysfunction
412Men diagnosed as having prostatitis often receive unnecessary antibiotics
412Practice Points
Which treatment should patients with high-risk T1G3 bladder cancer receive?
414doi:10.1038/ncpuro1149 | Full Text | PDF (128K)
Is tension-free vaginal tape as effective as colposuspension in the long-term treatment of stress urinary incontinence?
416doi:10.1038/ncpuro1152 | Full Text | PDF (129K)
What is the role of radiation dose escalation in the treatment of localized prostate cancer?
418doi:10.1038/ncpuro1153 | Full Text | PDF (127K)
Does radiofrequency ablation preserve long-term renal function in patients with small renal masses?
420doi:10.1038/ncpuro1156 | Full Text | PDF (128K)
Antiangiogenic therapy in renal cell carcinoma: a plethora of choices
422doi:10.1038/ncpuro1157 | Full Text | PDF (130K)
Viewpoint
Incorporating fluorescence cystoscopy for the diagnosis of bladder cancer into clinical practice
424In this Viewpoint article by Dr Karl and colleagues, the authors discuss the benefits of fluorescence cystoscopy for the diagnosis of transitional cell carcinoma of the bladder, which include reduced residual tumor rate and tumor recurrence rate, and enhanced detection of carcinoma in situ and multifocal tumors, when compared with white-light cystoscopy.
doi:10.1038/ncpuro1150 | Full Text | PDF (128K)
Reviews
How patients make treatment choices
426The availability of medical information has enabled many patients to become well informed about their disease, and thus active participants in their care. In this Review, Hellenthal and Ellison look at patient decision making as it pertains to the treatment of urologic disease. The authors demonstrate that patients consider adverse-effect profile, treatment invasiveness and treatment efficacy to be important treatment outcomes.
doi:10.1038/ncpuro1189 | Full Text | PDF (208K)
Bone imaging in prostate cancer
434Bone metastases are common among patients with primary breast, lung or prostate cancers. However, diagnosis of bone metastases can be difficult and is dependent on radiological evidence. In this Review, Zohar Dotan assesses the various imaging modalities that might be suitable for diagnosing bone metastases in patients with prostate cancer.
doi:10.1038/ncpuro1190 | Full Text | PDF (284K)
Circulating endothelial cells as biomarkers of prostate cancer
445Prostate cancer has a wide spectrum of biological aggressiveness, but characterization of prostate-cancer aggressiveness at the time of diagnosis can be difficult. Tumor vascularization positively correlates with disease progression and, therefore, markers of angiogenesis could be indicators of clinical outcomes. Circulating endothelial progenitors and circulating endothelial cells play an integral part in neovascularization, and in this Review the authors discuss the potential of these cells as prognostic indicators.
doi:10.1038/ncpuro1188 | Full Text | PDF (448K)
Case Studies
Urogenital tuberculosis in a patient with AIDS: an unusual presentation
455In patients with AIDS, urogenital tuberculosis presents both diagnostic and therapeutic challenges. In this Case Study, Figueiredo et al. present a 38-year-old man who was initially misdiagnosed as having a usual urinary tract infection. The authors use the patient to illustrate the unusual presentation and special treatment requirements of immunosuppressed patients with urogenital tuberculosis.
doi:10.1038/ncpuro1148 | Full Text | PDF (273K)
A case of systemic polyarteritis nodosa with spermatic cord involvement
462Polyarteritis nodosa is a rare systemic necrotizing vasculitis that requires urgent treatment. Asymptomatic scrotal involvement is relatively common, although symptomatic involvement is rarer. In this Case Study, Bush and colleagues highlight how urological evaluation including scrotal biopsy can enable rapid diagnosis of the disease and allow appropriate immunosuppressive therapy to be administered in a timely manner.
doi:10.1038/ncpuro1170 | Full Text | PDF (379K)
