Urology: a long history of innovation

Peter T Scardino

doi:10.1038/ncpuro1042 | Full Text | PDF (134K)

Gene therapy for the treatment of erectile dysfunction

Arnold Melman and Marc Feder

Although oral phosphodiesterase 5 inhibitors have substantially improved the treatment of erectile dysfunction, unmet needs among men with erectile dysfunction still exist. This article considers the possibility of gene therapy for these patients, and discusses results from early clinical studies of gene therapy for erectile dysfunction.

doi:10.1038/ncpuro1014 | Full Text | PDF (172K)

Low testosterone levels linked to increased mortality

doi:10.1038/ncpendmet0705 | Full Text | PDF (89K)

Upgrading prostate cancer patients with a Gleason score of 7 and tertiary grade 5 is warranted

doi:10.1038/ncponc1033 | Full Text | PDF (89K)

Reduced PSAV threshold is predictive of prostate cancer in men with serum PSA <4 ng/ml

doi:10.1038/ncpuro1001 | Full Text | PDF (99K)

ADT for prostate cancer could increase the risk of death from cardiovascular causes

doi:10.1038/ncpuro1002 | Full Text | PDF (88K)

Novel lateral-cutting resectoscope: a method for safer TUR?

doi:10.1038/ncpuro1003 | Full Text | PDF (88K)

Phase II trial demonstrates activity of axitinib against metastatic renal cell cancer

doi:10.1038/ncpuro1004 | Full Text | PDF (88K)

Tumor markers of testicular cancer underutilized in the US: a quality-of-care concern?

doi:10.1038/ncpuro1005 | Full Text | PDF (88K)

Mortality in men hospitalized with AUR: the effects of age and comorbidity

doi:10.1038/ncpuro1006 | Full Text | PDF (98K)

Yoga improves premature ejaculation

doi:10.1038/ncpuro1007 | Full Text | PDF (89K)

Repeat injections of botulinum A toxin effectively treat neurogenic detrusor overactivity

doi:10.1038/ncpuro1008 | Full Text | PDF (99K)

Retrograde urethrocystography might impair CT of hemorrhages in pelvic fracture patients

doi:10.1038/ncpuro1009 | Full Text | PDF (87K)

Hysterectomy is associated with an increased risk of future stress urinary incontinence

doi:10.1038/ncpuro1010 | Full Text | PDF (97K)

Many sexual adverse effects of finasteride are attributable to a nocebo effect

doi:10.1038/ncpuro1012 | Full Text | PDF (87K)

Increased onion and garlic intake is associated with a decreased risk of BPH

doi:10.1038/ncpuro1011 | Full Text | PDF (87K)

Is obesity associated with biochemical recurrence in patients with prostate cancer?

Andrew J Stephenson

doi:10.1038/ncpuro0989 | Full Text | PDF (173K)

What are the practitioner-level determinants for inappropriate PSA testing?

Freddie C Hamdy

doi:10.1038/ncpuro0990 | Full Text | PDF (171K)

Oral versus parenteral antibiotics for the initial treatment of a first episode of acute pyelonephritis in children

Martin A Koyle

doi:10.1038/ncpuro0996 | Full Text | PDF (179K)

Which pathological features of renal cell carcinoma have the greatest prognostic value?

Jeffrey La Rochelle and Arie S Belldegrun

doi:10.1038/ncpuro0997 | Full Text | PDF (172K)

Does patient age affect the stone-free rate in patients with urinary calculi treated with extracorporeal SWL?

Margaret S Pearle

doi:10.1038/ncpuro1000 | Full Text | PDF (172K)

Is high-dose chemotherapy effective in patients with relapsed or refractory germ cell tumors?

Darren R Feldman, Robert J Motzer and Dean F Bajorin

doi:10.1038/ncpuro0999 | Full Text | PDF (173K)

Does androgen deprivation therapy in men with prostate cancer increase cardiovascular morbidity?

Steven M Corsello and Philip W Kantoff

doi:10.1038/ncpuro1015 | Full Text | PDF (173K)

Predictive models and prostate cancer

Pierre I Karakiewicz and Georg C Hutterer

The use of nomograms for predicting tumor characteristics and outcomes in prostate cancer patients can be helpful in treatment decision-making. In this article the authors review several nomograms, developed since the observed stage migration in prostate cancer, that can be used to predict cancer prevalence at prostate biopsy, prognosis and pretreatment staging.

doi:10.1038/ncpuro0972 | Full Text | PDF (442K)

Balkan endemic nephropathy and associated urothelial cancer

Vladisav Stefanovic and Zoran Radovanovic

Balkan endemic nephropathy is a familial disorder that affects people living in the alluvial plains along the tributaries of the Danube River and has a strong association with upper urothelial carcinomas. Although thought to be declining in incidence, it still represents a notable problem and these authors suggest it might be more widespread than previously thought.

doi:10.1038/ncpuro1019 | Full Text | PDF (373K)