Localized prostate cancer is rarely a fatal disease

Peter T Scardino

doi:10.1038/ncpuro1013 | Full Text | PDF (131K)

Low-risk prostate cancer can and should often be managed with active surveillance and selective delayed intervention

Laurence Klotz

In this Viewpoint article, Professor Klotz argues that active surveillance of patients with low-risk prostate cancer, followed by intervention when pre-specified criteria are fulfilled, is an approach that could prevent unnecessary overtreatment of prostate cancer. Professor Klotz describes patients eligible for this approach, the strategy for active surveillance, and the criteria for intervention.

doi:10.1038/ncpuro0993 | Full Text | PDF (176K)

Radiotherapy and hormone therapy in patients with high-risk prostate cancer

doi:10.1038/ncponc0994 | Full Text | PDF (89K)

Plasma HER2 and EGFR levels are prognostic factors in patients with prostate cancer

doi:10.1038/ncponc0996 | Full Text | PDF (89K)

Prostatectomy confers the best chance of long-term prostate-cancer-specific survival

doi:10.1038/ncponc1013 | Full Text | PDF (99K)

The histone demethylase JHDM2A is essential for spermatogenesis in mice

doi:10.1038/ncpuro0977 | Full Text | PDF (88K)

Hemastix^® is a useful diagnostic tool for urinary schistosomiasis control programs

doi:10.1038/ncpuro0978 | Full Text | PDF (98K)

COX-2 overexpression might predict treatment failure in patients with prostate cancer

doi:10.1038/ncpuro0979 | Full Text | PDF (88K)

Cystectomy or conservative therapy for patients with high-risk, T1G3 bladder cancer?

doi:10.1038/ncpuro0982 | Full Text | PDF (99K)

Successful treatment of female SUI with autologous myoblast and fibroblast injection

doi:10.1038/ncpuro0980 | Full Text | PDF (99K)

Early treatment of urinary tract infection prevents renal involvement

doi:10.1038/ncpuro0981 | Full Text | PDF (89K)

Stress implicated in the etiology of benign prostatic hyperplasia

doi:10.1038/ncpuro0983 | Full Text | PDF (89K)

Transobturator method of treating SUI preserves normal clitoral blood flow

doi:10.1038/ncpuro0984 | Full Text | PDF (88K)

High survival rate after Mohs micrographic surgery for penile cancer

doi:10.1038/ncpuro0985 | Full Text | PDF (99K)

Undiagnosed BOO could result in renal damage in patients with Down syndrome

doi:10.1038/ncpuro0986 | Full Text | PDF (89K)

Reduced complications associated with seminal-vesicle-sparing perineal RP

doi:10.1038/ncpuro0987 | Full Text | PDF (89K)

Should patients with prostate cancer and a risk of nodal metastasis >1% undergo standard or limited PLND?

Urs E Studer

doi:10.1038/ncpuro0943 | Full Text | PDF (172K)

Is laparoscopic partial nephrectomy as effective as open partial nephrectomy in patients with renal cell carcinoma?

Paul Russo

doi:10.1038/ncpuro0938 | Full Text | PDF (173K)

Is cryopreservation of sperm effective for preserving fertility in adolescents and young adults with cancer?

James M Bresee and Harris M Nagler

doi:10.1038/ncpuro0967 | Full Text | PDF (176K)

Can indices determine the pathogenesis of age-related nocturia?

Timothy Boone

doi:10.1038/ncpuro0969 | Full Text | PDF (167K)

Is CT-guided percutaneous radiofrequency ablation oncologically effective in patients with renal cell carcinoma?

Robert G Uzzo

doi:10.1038/ncpuro0975 | Full Text | PDF (175K)

Is penile length after radical prostatectomy affected by nerve-sparing status and recovery of erectile function?

John Mulhall

doi:10.1038/ncpuro0974 | Full Text | PDF (174K)

Is radical radiotherapy effective in patients with pT1G3 NXM0 bladder cancer?

Harry W Herr

doi:10.1038/ncpuro0976 | Full Text | PDF (170K)

Androgen-deprivation-therapy-induced fractures in men with nonmetastatic prostate cancer: what do we really know?

Celestia S Higano

Androgen deprivation therapy (ADT) for prostate cancer is associated with decreased bone mineral density (BMD) in patients. This decreased BMD can lead to an increased risk of fractures and osteoporosis. In this article the author reviews the prevalence of bone loss in this group of patients, and discusses the implications of reduced BMD and what can be done to prevent or reduce bone loss in men undergoing ADT.

doi:10.1038/ncpuro0995 | Full Text | PDF (434K)

Surgical management of large renal tumors

Matthew F Wszolek, Chad Wotkowicz and John A Libertino

Large renal tumors of 7 cm or more in size are associated with important challenges in management. In this Review the authors discuss the different surgical management options for patients with these large tumors. Important complicating factors such as tumor thrombus are discussed and the authors also examine the use of partial nephrectomy in patients with T2 renal tumors.

doi:10.1038/ncpuro0963 | Full Text | PDF (811K)

Primer: cognitive motor learning for teaching surgical skill—how are surgical skills taught and assessed?

Jaime A Wong and Edward D Matsumoto

The process of learning surgical skills is long, complex and involves numerous stages. The authors of this Review discuss the different processes involved in learning and assessing surgical techniques. They highlight the role of surgical simulators in training surgeons in new techniques and how they might help to improve trainee surgeons' performance and patient outcomes.

doi:10.1038/ncpuro0991 | Full Text | PDF (310K)

A case of prostatic adenocarcinoma recurrence presenting as ductal carcinoma of the prostate

William H Tu, Kristin Jensen, Fuad Freiha and Joseph C Liao

In this Case Study, Tu et al. report on a 61-year-old man previously treated for prostatic adenocarcinoma who presented with obstructive urinary symptoms and was subsequently found to have ductal carcinoma of the prostate. The authors discuss the difficulty of diagnosing this tumor, and the correct approach to its management.

doi:10.1038/ncpuro0994 | Full Text | PDF (436K)