Use of antibiotics in pediatric urology

Alexandra M Hay

doi:10.1038/ncpuro0908 | Full Text | PDF (95K)

Risk of transmission of genetic diseases by assisted reproduction

Larry I Lipshultz and Dolores J Lamb

Male factor infertility is currently difficult to diagnose and counseling patients can be challenging. After years of research into endocrine control of spermatogenesis, researchers are now investigating the genes required for male fertility. In this Viewpoint the authors discuss the major advances in the ability to diagnose genetic defects in infertile males.

doi:10.1038/ncpuro0879 | Full Text | PDF (135K)

Temsirolimus prolongs survival of patients with metastatic renal cell carcinoma

doi:10.1038/ncpuro0862 | Full Text | PDF (104K)

The effect of cleaning on midstream urine collection contamination in children

doi:10.1038/ncpuro0863 | Full Text | PDF (90K)

A nomogram to predict seminal vesicle invasion in prostate cancer patients

doi:10.1038/ncpuro0864 | Full Text | PDF (100K)

Radiographic bladder assessment is indicated by gross but not microscopic hematuria

doi:10.1038/ncpuro0865 | Full Text | PDF (104K)

Fluorescence cystoscopy improves diagnosis of bladder cancer

doi:10.1038/ncpuro0866 | Full Text | PDF (101K)

Inflammatory pseudotumors in bladder cancer patients

doi:10.1038/ncpuro0867 | Full Text | PDF (105K)

Modest efficacy of ixabepilone as second-line chemotherapy in patients with HRPC

doi:10.1038/ncpuro0868 | Full Text | PDF (91K)

Tramadol shows impressive results for men with premature ejaculation

doi:10.1038/ncpuro0870 | Full Text | PDF (124K)

Biochemical recurrence is not affected by delayed treatment for prostate cancer

doi:10.1038/ncpuro0871 | Full Text | PDF (105K)

Androgen suppression therapy increases the risk of myocardial infarction in older men

doi:10.1038/ncpuro0872 | Full Text | PDF (100K)

Collagen XXIII—a promising biomarker for prostate cancer metastasis

doi:10.1038/ncponc0867 | Full Text | PDF (100K)

Transobturator routes for suburethral tape placement not superior to retropubic insertion

doi:10.1038/ncpuro0873 | Full Text | PDF (105K)

Low testosterone levels in boys conceived using intra-cytoplasmic sperm injection

doi:10.1038/ncpendmet0565 | Full Text | PDF (88K)

JM-27 levels can distinguish between different forms of benign prostatic hyperplasia

doi:10.1038/ncponc0833 | Full Text | PDF (104K)

Molecular pathways and the hope of targeting angiogenesis

Cora N Sternberg

doi:10.1038/ncpuro0858 | Full Text | PDF (138K)

Untethering of the spinal cord in children with myelomeningocele: effect on bladder function

David B Joseph

doi:10.1038/ncpuro0876 | Full Text | PDF (133K)

The optimal management of clinically localized prostate cancer: the debate continues

Marc Dall'Era and Badrinath Konety

doi:10.1038/ncpuro0880 | Full Text | PDF (134K)

Is tension-free vaginal tape more effective than laparoscopic colposuspension for stress incontinence?

Sushma Srikrishna, Dudley Robinson and Linda Cardozo

doi:10.1038/ncpuro0882 | Full Text | PDF (135K)

Is transurethral microwave thermotherapy comparable to transurethral resection for BPH?

Alexis E Te

doi:10.1038/ncpuro0881 | Full Text | PDF (138K)

How useful is PSA velocity as a screening tool for prostate cancer detection?

Christopher R Porter

doi:10.1038/ncpuro0886 | Full Text | PDF (130K)

Can the AJCC staging system risk-stratify patients with localized prostate cancer?

Georg C Hutterer and Pierre I Karakiewicz

doi:10.1038/ncpuro0885 | Full Text | PDF (135K)

Interstitial cystitis and systemic autoimmune diseases

Joop P van de Merwe

Interstitial cystitis is a chronic disease of unknown origin, for which definitive diagnostic criteria remain undecided. Various epidemiological characteristics of interstitial cystitis suggest an autoimmune nature to this disorder, and clinical associations have been made with generalized autoimmune diseases, among other disease. This Review discusses these autoimmune associations and various possible causal mechanisms.

doi:10.1038/ncpuro0874 | Full Text | PDF (282K)

Current management strategies for testicular microlithiasis

Kirubanand Jaganathan, Shwan Ahmed, Alastair Henderson and Abhay Rané

The frequency of testicular microlithiasis detection has increased as imaging technologies have advanced. Associations have been made between this and various other testicular disorders, including cancer, but the causative nature of the relationship is unclear. This Review assesses the evidence for associations with testicular tumors, infertility and other benign scrotal pathologies, and how to manage patients.

doi:10.1038/ncpuro0856 | Full Text | PDF (245K)

Advances in imaging for urologic procedures

Jonathan Coleman, Rodrigo Nascimento and Stephen B Solomon

Developments in medical imaging have driven advances in minimally invasive surgery, and image-guidance is now an integral part of many urological procedures. This Review discusses developments in imaging technologies such as fluoroscopic imaging, molecular imaging, image fusion and four-dimensional ultrasonography, and their applications in urological practice.

doi:10.1038/ncpuro0883 | Full Text | PDF (321K)

Prostate biopsy strategies

Joseph C Presti Jr

There is much debate about which biopsy strategy is best to use in patients with suspected prostate cancer. In this Review the different biopsy templates are discussed in relation to their use for an initial prostate biopsy in men identified by PSA screening or an abnormal digital rectal examination and repeat biopsies.

doi:10.1038/ncpuro0887 | Full Text | PDF (308K)