Table of contents
June 2007 Volume 4 No 6
Viewpoints
Losing the kingdom: the case against commercial organ donation
290In the first of two Viewpoint articles to discuss the ethical and practical implications of commercial kidney donation, the author argues that—despite the dearth of suitable organs available for transplantation—we as a society cannot afford to compromise on ethics.
Kidney donation and rewarded gifting: an Iranian model
292In the second of two Viewpoint articles discussing the ethical and practical implications of commercial kidney donation, the author explains how the Iranian model of rewarded gifting for living kidney donation has revolutionized the transplantation process by completely eliminating waiting lists.
Research Highlights
Risk of death from prostate cancer increases as time to androgen suppression increases
294Adding calcitriol to docetaxel results in a valuable survival benefit
294New method for measuring serum PSA level might enable mass screening programs
294Brachytherapy plus EBRT reduces the risk of ECE in prostate cancer patients
295Once-weekly oral alendronate prevents bone loss in men receiving ADT for prostate cancer
295
-Blocker treatment promotes ureteral stone expulsion
296Modified RPLND templates can miss residual testicular cancer
296New procedure for endoscopic decompression of ectopic ureterocele shows promise
297Adjuvant, intravesical BCG therapy is cost-effective
297The goal of therapy for ED should be maximal erection hardness
297Testis-derived transcript gene variants and prostate cancer risk in black men
298Transurethral needle ablation of the prostate has poor long-term efficacy
298Risk of renal failure after bariatric surgery in patients with kidney stones
299Practice Points
Nephron-sparing surgery: the 'gold standard' treatment for small renal cortical tumors
300Do dehydroepiandrosterone supplements have anti-aging potential?
302Does ofloxacin protect against BCG-related toxic effects in patients with bladder cancer?
304Is uroflowmetry necessary following hypospadias repair?
306Reviews
Drug Insight: the use of bisphosphonates for the prevention and treatment of osteoporosis in men
310Men with hypogonadism and those undergoing androgen deprivation treatments for prostate cancer are at an increased risk of developing osteoporosis. Bisphophonates are important in the treatment of, and protection against, osteoporosis. This article discusses the use of different bisphosphonates in this patient population, including their mechanisms of action, efficacy and safety.
doi:10.1038/ncpuro0816 | Full Text | PDF (588K)
Mechanisms of Disease: high-grade prostatic intraepithelial neoplasia and other proposed preneoplastic lesions in the prostate
321Various findings in prostate tissue indicate raised risk of later prostate cancer, and, of all these, the finding of high-grade prostatic intraepithelial neoplasia on repeated biopsy is most strongly associated. This Review discusses the morphologic spectrum and clinical importance of these proposed preneoplastic lesions and conditions of the prostate, especially high-grade prostatic intraepithelial neoplasia.
doi:10.1038/ncpuro0815 | Full Text | PDF (720K)
Therapy insight: prophylaxis, monitoring and treatment of perioperative myocardial ischemia with emphasis on urological surgery
333Perioperative myocardial ischemia is common in patients who undergo high-risk surgery, and might be predictive of postoperative cardiac morbidity or mortality. In this Review the authors discuss the diagnosis, monitoring and prophylaxis of perioperative myocardial ischemia and infarction in patients undergoing major urological surgery.
doi:10.1038/ncpuro0817 | Full Text | PDF (211K)
