Table of contents
May 2007 Volume 4 No 5
Editorial
Viewpoint
The importance of crossing vessels in ureteropelvic junction obstruction
232With the popularization of laparoscopic and robotic pyeloplasty has come a resurgence in the debate over the role of crossing vessels in the pathogenesis of UPJ obstruction. In this Viewpoint, the authors examine the evidence and argue that crossing vessels are implicated in the etiology of UPJ obstruction and are important because of their potential to lead to cause surgical complications if they are not recognized.
Research Highlights
Continence rates should be interpreted with caution in patients with overactive bladder
234Percutaneous renal core biopsy results should influence treatment of patients
234Intracavernosal injection results in accurate measurement of penile curvature
234Topical eutectic lidocaine–prilocaine mixture delays premature ejaculation
235Some patients with low detrusor contractility benefit from BTX-A injections
236Apoptosis biomarkers could aid prediction of outcome after surgery for bladder cancer
236Long-term follow-up of true hermaphroditism cases treated by conservative surgery
237Laparoscopic and open radical prostatectomy have equivalent urinary outcomes
237Serum biomarker JM-27 could distinguish symptomatic from asymptomatic BPH
237Survivors of testicular cancer have an increased risk of second malignancy
238Only trained and experienced medical personnel should perform circumcisions
238High prevalence of ghost authorship in industry-initiated trials
239Practice Points
Does difluoromethylornithine prevent recurrence in low-risk superficial bladder cancer?
240Mid-urethral slings: surgical evolution as manifest by technology
242Is initial or delayed nephrectomy the optimal treatment for nonmetastatic Wilms' tumor?
244Effectiveness of topical steroid treatment for phimosis
246Will a new intravesical chemotherapy agent improve the treatment of non-muscle-invasive bladder cancer?
248Is hysterectomy associated with an increase in the symptoms of urinary incontinence?
250Reviews
The management of superficial bladder cancer
254This Review discusses the management of nonmuscle invasive bladder cancer. Approaches to intravesical chemotherapy are described, including the impact of chemotherapy on the recurrence and progression of tumors. The effect of intravesical immunotherapy in bladder cancer is also explored, as well as the role of early cystectomy.
doi:10.1038/ncpuro0784 | Full Text | PDF (206K)
Ablative techniques for the management of kidney cancer
261Probe-ablative techniques for small kidney cancer lesions are being investigated as alternatives to partial nephrectomy in selected patients. Advances in imaging guidance that are improving outcomes and the minimally invasive nature make this approach to therapy attractive. This Review provides a critical evaluation of the advantages and disadvantages of these techniques.
doi:10.1038/ncpuro0802 | Full Text | PDF (348K)
Candidate genes and their response to environmental agents in the etiology of hypospadias
270An unexplained increase in the prevalence of the congenital anomaly hypospadias led researchers to investigate the molecular events and genetic expression that underlie this disorder. This Review provides an overview of findings in mice and humans that relate to urethral development, candidate genes and steroid receptor expression, and describes the influence of environmental triggers.
doi:10.1038/ncpuro0783 | Full Text | PDF (538K)
Case Studies
Successful treatment with botulinum toxin A after failed augmentation ileocystoplasty
280doi:10.1038/ncpuro0799 | Full Text | PDF (492K)
A case of Castleman's disease that presented as a retroperitoneal mass
285doi:10.1038/ncpuro0800 | Full Text | PDF (304K)
