Practice Point

Nature Clinical Practice Urology (2007) 4, 656-657
doi:10.1038/ncpuro0945  
Received 5 August 2007 | Accepted 18 September 2007 | Published online: 16 October 2007

Does tumor location affect renal function after partial nephrectomy?

Mihir M Desai

Correspondence Section of Endourology and Stone Disease, Glickman Urological Institute/A100, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA

Email
 desaim1@ccf.org

This article has no abstract so we have provided the first paragraph of the full text.

The past few decades have established nephron-sparing surgery (NSS) as the standard treatment modality for patients with small renal masses. Currently, partial nephrectomy remains the gold-standard NSS option. NSS has become more relevant with the rising incidence of renal cell carcinoma and the increased detection of incidental tumors by abdominal CT or MRI. The current status of partial nephrectomy is the result of several evolutionary stages of NSS, and this evolution is ongoing. The initial step was the transition of partial nephrectomy from a procedure reserved for emergent indications, such as tumor in a solitary kidney or bilateral tumors, to a procedure of choice in patients with a normal contralateral kidney. This step resulted from data that demonstrated oncologic equivalence and a substantial renal function advantage after partial nephrectomy compared with radical nephrectomy.1, 2

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