Practice Point

Nature Clinical Practice Urology (2007) 4, 654-655
doi:10.1038/ncpuro0966  
Received 3 August 2007 | Accepted 1 October 2007 | Published online: 30 October 2007

Does RPLND improve outcomes in men with intermediate-risk and high-risk germ cell tumors?

Daniel W Lin

Correspondence Department of Urology, Box 356510, 1959 NE Pacific Street, University of Washington, Seattle, WA 98195, USA

Email
 dlin@u.washington.edu

This article has no abstract so we have provided the first paragraph of the full text.

While cisplatin-based chemotherapy for patients with advanced GCTs has yielded remarkable advancements in overall survival, a substantial proportion of men who initially present with metastatic disease will have persistent residual masses after chemotherapy. Models have been developed to predict the histology of these masses, and thus obviate postchemotherapy surgery in low-risk patients;1, 2 however, controversy remains over whether these models predict histology with acceptable accuracy. This study by Shayegan et al. adds information on the effectiveness of chemotherapy and the importance of surgery.

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