Table of contents

November 2007 Volume 4 No 11

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Editorial

Living beyond cancer: survivorship is more than surviving

Mary S McCabe

575

doi:10.1038/ncpuro0947 | Full Text | PDF (125K)


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Viewpoint

Limitations and use of PSA velocity in the diagnosis and characterization of prostate cancer

Andrew D Smith and John L Phillips

576

Measuring PSA velocity to track prostatic pathophysiologic states is appealing for its simplicity, however, much debate continues as to its clinical value in the diagnosis and characterization of prostate cancer. Phillips and Smith discuss the significance of PSA velocity as a diagnostic measure.

doi:10.1038/ncpuro0936 | Full Text | PDF (159K)


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Research Highlights

Patient anxiety influences prostate cancer treatment decisions

578

doi:10.1038/ncpuro0920 | Full Text | PDF (103K)

Is surgical outcome for prostate cancer patients associated with a surgeon's experience?

578

doi:10.1038/ncpuro0921 | Full Text | PDF (103K)

Ageing is associated with poorer ESWL outcomes in patients with renal calculi

578

doi:10.1038/ncpuro0922 | Full Text | PDF (113K)

B7-H3 expression level predicts prostate cancer progression following surgery

579

doi:10.1038/ncpuro0923 | Full Text | PDF (104K)

Increased use of ICSI for treatment of infertility other than male-factor infertility

579

doi:10.1038/ncpuro0924 | Full Text | PDF (114K)

Increased risk of cardiovascular morbidity in men with prostate cancer who receive ADT

580

doi:10.1038/ncpuro0926 | Full Text | PDF (104K)

Treatment with baclofen improves dysfunctional voiding in women

580

doi:10.1038/ncpuro0927 | Full Text | PDF (104K)

Testosterone has clinical benefit for postmenopausal hypoactive sexual desire disorder

581

doi:10.1038/ncpuro0925 | Full Text | PDF (103K)

Chromogranin A predicts development of hormone-refractory prostate cancer

581

doi:10.1038/ncpuro0928 | Full Text | PDF (103K)

Higher incidence of genitourinary anomalies in girls with congenital adrenal hyperplasia

581

doi:10.1038/ncpuro0929 | Full Text | PDF (115K)

Deflux® injection reduces UTI incidence in children with VUR

582

doi:10.1038/ncpuro0930 | Full Text | PDF (105K)

Sorafenib plus IFN-alpha is superior to single-agent therapy for metastatic RCC

582

doi:10.1038/ncpuro0931 | Full Text | PDF (105K)

A novel regimen for poor-prognosis or relapsed germ cell tumors

583

doi:10.1038/ncponc0947 | Full Text | PDF (103K)

Discontinuation of therapy in men with idiopathic hypogonadotropic hypogonadism

583

doi:10.1038/ncpuro0948 | Full Text | PDF (103K)


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Practice Points

Should patients with prostate cancer without bone metastases receive sodium clodronate?

Fred Saad

584

doi:10.1038/ncpuro0911 | Full Text | PDF (160K)

Is temsirolimus more safe and effective than interferon alpha for the treatment of advanced renal cell carcinoma?

Ali-Reza Golshayan and Ronald M Bukowski

586

doi:10.1038/ncpuro0915 | Full Text | PDF (169K)

Should patients with high-risk prostate cancer receive 6 months or 3 years of adjuvant androgen suppression therapy?

Seth Strope and David P Wood

588

doi:10.1038/ncpuro0932 | Full Text | PDF (163K)

Is genitourinary imaging necessary in patients who have microscopic hematuria after trauma?

Bryan B Voelzke and Jack W McAninch

590

doi:10.1038/ncpuro0919 | Full Text | PDF (159K)

Should physicians use the updated Partin tables to predict pathologic stage in patients with prostate cancer?

Michael W Kattan

592

doi:10.1038/ncpuro0940 | Full Text | PDF (161K)

A new nomogram for predicting seminal vesicle invasion at radical prostatectomy

Eric A Klein

594

doi:10.1038/ncpuro0937 | Full Text | PDF (173K)


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Reviews

Organ-sparing treatment for penile cancer

Alberto A Antunes, Marcos F Dall'Oglio and Miguel Srougi

596

Radical surgery for penile carcinoma produces good cure rates, but severely impacts on patients' quality of life. For a select group of patients, conservative treatments can be a suitable alternative producing good cure rates without such a negative impact on quality of life. In this Review, the different organ-sparing treatments for penile carcinoma are discussed, along with their suitability for patients with cancers of different stages.

doi:10.1038/ncpuro0918 | Full Text | PDF (309K)

The effect of body mass index on PSA levels and the development, screening and treatment of prostate cancer

Ted A Skolarus, Kathleen Y Wolin and Robert L Grubb III

605

There has been much research examining the relationship between body mass index (BMI) and the risk of developing prostate cancer and disease progression. Despite the number of studies, it has been difficult to establish how BMI might influence cancer risk and development. This Review article discusses the available data on BMI and obesity, and how these factors might influence the risk of developing prostate cancer, cancer screening and treatment.

doi:10.1038/ncpuro0944 | Full Text | PDF (341K)

Surgery Insight: surgical management of postprostatectomy incontinence—the artificial urinary sphincter and male sling

Craig V Comiter

615

Following prostatectomy, many men suffer with urinary incontinence. Stress urinary incontinence (SUI) can continue to be bothersome in some men, even after treatment with conservative therapies. In this article the surgical treatments for male SUI are reviewed. The suitability and efficacy of both the artificial urinary sphincter and the more recently introduced male sling are discussed in detail.

doi:10.1038/ncpuro0935 | Full Text | PDF (379K)


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Case Studies

Continuing Medical Education

Laparoscopic pyeloplasty in a solitary kidney

Nauman Zafar, John Leyland and Nimish C Shah

625

This Case Study describes a 40-year-old man who presented with abdominal pain without lower urinary tract symptoms. Following investigations, including abdominal CT and MAG3 renogram, ureteropelvic junction obstruction was confirmed. In this Case Study the diagnostic work-up in this patient and their management with laparoscopic transperitoneal dismembered Anderson–Hynes pyeloplasty is described.

doi:10.1038/ncpuro0961 | Full Text | PDF (356K)

Modern management of pheochromocytoma

Sanjay Kasturi, Alexander Kutikov, Thomas J Guzzo, Ariana L Smith and Alan J Wein

630

This Case Study describes a 55-year-old man with a history of coronary artery disease who was diagnosed with pheochromocytoma of the left adrenal gland. The authors discuss the diagnosis of this patient and his treatment with alpha-blockade therapy combined with phenoxybenzamine before open adrenalectomy.

doi:10.1038/ncpuro0962 | Full Text | PDF (242K)


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