Oral antibiotics alone can be used to treat pediatric acute pyelonephritis
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Current guidelines recommend that children with acute pyelonephritis are initially treated with a parenteral third-generation cephalosporin such as ceftriaxone, and then oral antibiotics. A recent noninferiority trial has found, however, that oral antibiotics alone are just as effective as the recommended regime, a finding that will potentially lower costs and reduce the discomfort of children with pyelonephritis.
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