Table of contents
February 2006 Volume 3 No 2
Viewpoints
Prevention of retrograde stone migration during ureteroscopy
60Retrograde stone migration during ureteroscopy leads to longer operating times, more-invasive endoscopy, and an increase in residual stones and the need for secondary procedures. In this Viewpoint, the author describes his experience with the various devices developed to prevent stone migration, focusing on the Stone Cone.
Transobturator versus retropubic suburethral tapes for stress urinary incontinence
62This Viewpoint provides a concise overview of transobturator and retropubic techniques for the surgical treatment of female stress urinary incontinence. The authors focus on a new generation of minimally invasive devices for sling placement, including the transvaginal tape and their own distal urethral polypropylene sling.
Research Highlights
Ultrasound-targeted needle biopsy could improve detection of prostate cancer
64Stone-to-skin distance predicts success of shock-wave lithotripsy for kidney stones
64Preoperative PSA kinetics predict prostate cancer outcomes
64No association found between vaginal birth and urinary incontinence
65Reducing the gynecomastia and breast pain associated with bicalutamide therapy
66A 2 cm excision margin is unnecessary for oncologic control in penile carcinoma
66Ciclosporin is successful in the treatment of interstitial cystitis
67Phase II trial shows carboxyamidotriazole is ineffective in refractory RCC
67Tadalafil preferred to sildenafil as treatment for erectile dysfunction
68Tumor grade and EGFR expression predict disease stage in urine ThinPrep® specimens
68HRT can cause urinary incontinence in older postmenopausal women
69Practice Points
Does postoperative adjuvant radiotherapy reduce biochemical progression after radical prostatectomy?
70Can an erectogenic pharmacotherapy regimen after radical prostatectomy improve postoperative erectile function?
72What are the operating characteristics of PSA screening for prostate cancer?
74Extracorporeal shock-wave lithotriptors: why newer may not be better
76Comparison of biochemical progression rates after radical prostatectomy and radiotherapy for localized prostate cancer
78Is a combination of alarm and drug therapies effective in nocturnal enuresis?
80
2a improve survival in patients with metastatic RCC?Reviews
How, why and when should urologists evaluate male sexual function?
84A goal-directed approach to managing men with male sexual dysfunction is important in order to fully understand the biological and psychological dimensions of each patient's condition. The evaluation and management of men presenting with symptoms of sexual dysfunction, and those with urologic problems and comorbid conditions that are associated with sexual problems, are discussed in this Review.
doi:10.1038/ncpuro0406 | Full Text | PDF (203K)
Surgery Insight: advantages and pitfalls of surgical techniques for the correction of bladder exstrophy
95Patients with bladder exstrophy present a challenge to urologists specializing in reconstruction. There are several different techniques by which repair can be achieved, each with their own associated success rates and morbidities. This article compares the techniques of staged reconstruction and complete primary repair of bladder exstrophy, highlighting the relative advantages and disadvantages associated with each method.
doi:10.1038/ncpuro0407 | Full Text | PDF (130K)
Mechanisms of Disease: the role of nerve growth factor in the pathophysiology of bladder disorders
101Elevated levels of nerve growth factor (NGF) in the bladders of patients with idiopathic overactive bladder syndrome, interstitial cystitis and benign prostatic hyperplasia has pointed to a role for NGF in the pathogenesis of lower urinary tract diseases. This article discusses the biology of NGF, its production in the bladder, and the mechanisms underlying its role in disorders of the lower urinary tract.
doi:10.1038/ncpuro0408 | Full Text | PDF (259K)
Case Study
Treatment of Peyronie's disease with oral pentoxifylline
111doi:10.1038/ncpuro0409 | Full Text | PDF (173K)
