Table of contents
January 2006 Volume 3 No 1
Editorial
Viewpoints
Open partial nephrectomy: an essential contemporary operation
2This Viewpoint documents recent developments in the field of renal cortical tumors, focusing on the current status of open partial nephrectomy. The author argues that nephron-sparing surgery is under-utilized, and that the current trend for urologic surgeons to adopt laparoscopic radical nephrectomy as a minimally invasive alternative could have important consequences for overall renal function.
Prostate cancer: risks and benefits of screening
4Screening for diseases is a fact of modern medicine. For prostate cancer, the issue is complex, as the overall benefit to patients is far from clear. In this Viewpoint, the advantages of early detection and treatment with PSA screening are weighed up against the risks of overdiagnosis and unnecessary treatment.
Research Highlights
HER-2/neu peptide vaccine for the prevention of prostate cancer recurrence
6Patterns of PDE5 inhibitor use in patients with erectile dysfunction
6Prostate size: association with disease severity and risk of postsurgical progression
6Accurate urine telomerase test for detecting bladder cancer
7Delaying surgery does not affect biochemical recurrence for clinically localized prostate cancer
7Y chromosome microdeletion confers susceptibility to testicular germ cell tumor
8Promising chemotherapy regimen for hormone-refractory prostate cancer
8
Testosterone therapy improves sexual function in postmenopausal women
9New study casts doubt on the 'free-hormone' hypothesis of sex-hormone uptake
9A new algorithm for the treatment of ureteropelvic junction obstruction
10Experience counts: MRI-based prostate-cancer staging
10Kidney paired donation: the answer for patients with incompatible live donors?
11doi:10.1038/ncpneph0046 | Full Text | PDF (100K)
Practice Points
Is pretreatment PSA velocity associated with prostate-cancer-specific mortality rate after radiotherapy?
12How does the retroperitoneoscopic approach to living-donor nephrectomy compare with the standard open procedure?
14Does weight loss improve urinary incontinence in overweight and obese women?
16Androgen deprivation plus conformal radiotherapy for prostate cancer: effects on morbidity
18Is microsurgical intussusception vasoepididymostomy a suitable option for men with obstructive azoospermia?
20Reviews
Prophylactic use of antimicrobials in commonly performed outpatient urologic procedures
24Some patients are at an increased risk of developing infection when undergoing outpatient procedures and, as a result, may require antimicrobial prophylaxis. A thorough assessment of patient risk factors is, therefore, essential. In this article the indications for prophylactic use of antibiotics in commonly performed outpatient urologic procedures and the different treatment regimens are reviewed.
doi:10.1038/ncpuro0357 | Full Text | PDF (157K)
Indications and contraindications for the use of laparoscopic surgery for renal cell carcinoma
32The laparoscopic approach for treating renal tumors has become standard practice in many medical centers, and while there are no absolute contraindications to performing laparoscopic renal surgery a number of factors should be considered when making treatment decisions. This review presents the indications and contraindications for the use of laparoscopic radical and partial nephrectomy for the treatment renal cell carcinoma.
doi:10.1038/ncpuro0384 | Full Text | PDF (144K)
Urodynamic assessment of bladder-outlet obstruction in women
38Although bladder-outlet obstruction (BOO) in women is an increasingly common problem, there are currently no accepted criteria used to define this type of bladder dysfunction. This review discusses the different symptoms associated with BOO in women and the role of urodynamic testing in diagnosis. Iatrogenic BOO following incontinence surgery is also discussed.
doi:10.1038/ncpuro0378 | Full Text | PDF (196K)
The management of interstitial cystitis: an update
45Interstitial cystitis (IC) is a poorly understood chronic condition that is difficult to diagnose and treat. The most characteristic symptom of IC is debilitating pelvic pain. This article reviews the different oral agents and other nonsurgical therapies that are available for the treatment IC, with particular emphasis on the management of pain associated with IC.
doi:10.1038/ncpuro0385 | Full Text | PDF (178K)
