Table of contents
November 2005 Volume 2 No 11
Editorial
Viewpoint
Percutaneous cryoablation of renal tumors: limitations and uncertainties
518Ablative modalities are gaining currency as viable treatment options in selected renal cancer patients, but outcome data remain relatively premature. In this Viewpoint, John Pattaras and Fray Marshall discuss the limitations and uncertainties surrounding one of the most studied modalities for renal tumor ablation.
Research Highlights
Ankle position, pelvic tilt and pelvic floor muscle activity in stress urinary incontinence
520The psychological benefits of sperm cryopreservation before chemotherapy
521Long-term risks of cancer in men with Klinefelter syndrome
521A role for death receptors in BCG therapy for bladder cancer?
522Risk of contralateral testicular cancer: to biopsy or not to biopsy?
522Vardenafil compared with papaverine in penile Doppler ultrasonography
523Randomized controlled trial suggests healthy living could slow progression of prostate cancer
523Antiandrogen and vaccine therapy for hormone-refractory prostate cancer
524NAT2 and GSTM1 polymorphisms affect the risk of bladder cancer
525Practice Points
Will the Prostate Cancer Prevention Trial affect population mortality rates?
526Can renal tumors be managed effectively with laparoscopic cryoablation?
528Is botulinum toxin type A a safe and effective treatment for neurogenic urinary incontinence?
530Ureteroscopic or extracorporeal shock-wave lithotripsy for distal ureteral stones in children?
532Can chronic pelvic pain in men be treated with myofascial trigger point release and paradoxical relaxation training?
534Reviews
What is the place of internal urethrotomy in the treatment of urethral stricture disease?
538In this article by André Naudé and Chris Heyns the controversial issue of management of urethral strictures is tackled. The authors review the relative efficacy and suitability of internal urethrotomy, dilation and urethroplasty for treatment of different types of stricture. An algorithm for the initial management of strictures and treatment of recurrent strictures is included.
doi:10.1038/ncpuro0320 | Full Text | PDF (166K)
Mechanisms of Disease: specialized interstitial cells of the urinary tract—an assessment of current knowledge
546There is growing evidence that interstitial cells play a functional role in the urinary tract. This review by Alison Brading and Karen McCloskey focuses on what is known about specialized interstitial cells, their underlying physiology and their possible roles in regulating smooth-muscle activity and neural control in the urinary tract. The involvement of these cells in bladder pathology is also discussed.
doi:10.1038/ncpuro0340 | Full Text | PDF (560K)
Primer: questionnaires versus urodynamics in the evaluation of lower urinary tract dysfunction—one, both or none?
555When seeking a diagnosis in patients complaining of lower urinary tract symptoms there is a bewildering variety of questionnaires, symptom scales, measurements and urodynamic tests that can be utilized. The appropriate use of these different diagnostic tools and their associated strengths and weaknesses are discussed in this primer review by Christopher Chapple.
doi:10.1038/ncpuro0339 | Full Text | PDF (154K)
Case Study

The importance of MRI evaluation in the preoperative work-up of prostate cancer
565doi:10.1038/ncpuro0328 | Full Text | PDF (2,099K)

