Mechanisms of Disease: genetic and epigenetic alterations that drive bladder cancer
Erika M Wolff, Gangning Liang and Peter A Jones*
Correspondence *Keck School of Medicine, University of Southern California, 1441 Eastlake Ave, Room 8302L, MC-9181, Los Angeles, CA 90089, USA
Email jones_p@ccnt.hsc.usc.edu
There are a number of factors that can influence a person's risk of developing cancer. In this review focussing on transitional cell carcinoma of the bladder, Erika Wolff and colleagues discuss the genes and molecular pathways implicated in the development of bladder cancer. Models for both the mechanisms behind bladder carcinogenesis and its progression are presented.
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