Nature Clinical Practice Urology Nature Clinical Practice Urology provides urologists with authoritative and timely interpretations of key developments in the field, translating the latest findings into clinical practice. http://www.nature.com/ncpuro/current_issue/ Nature Publishing Group en © 2008 Nature Publishing Group Nature Clinical Practice Urology 1743-4270 1743-4289 © 2008 Nature Publishing Group permissions@nature.com Nature Clinical Practice Urology http://www.nature.com/includes/rj_globnavimages/ncpuro_logo.gif http://www.nature.com/ncpuro/ Plagiarism: cutting out cut-and-paste jobs http://dx.doi.org/10.1038/ncpuro1169 Plagiarism: cutting out cut-and-paste jobs

Nature Clinical Practice Urology 5, 351 (2008). doi:10.1038/ncpuro1169

Author: Nayanah Siva

]]> Plagiarism: cutting out cut-and-paste jobs Nayanah Siva doi:10.1038/ncpuro1169 Nature Clinical Practice Urology 5, 351 (2008) Nature Clinical Practice Urology 5 7 Editorial 351 351 Optimum management of emphysematous pyelonephritis: a systematic review http://dx.doi.org/10.1038/ncpuro1135 Optimum management of emphysematous pyelonephritis: a systematic review

Nature Clinical Practice Urology 5, 352 (2008). doi:10.1038/ncpuro1135

]]> Optimum management of emphysematous pyelonephritis: a systematic review doi:10.1038/ncpuro1135 Nature Clinical Practice Urology 5, 352 (2008) Nature Clinical Practice Urology 5 7 Research Highlights 352 352 The poppy-seed test is a cheap and accurate diagnostic tool for colovesical fistula http://dx.doi.org/10.1038/ncpuro1136 The poppy-seed test is a cheap and accurate diagnostic tool for colovesical fistula

Nature Clinical Practice Urology 5, 352 (2008). doi:10.1038/ncpuro1136

]]> The poppy-seed test is a cheap and accurate diagnostic tool for colovesical fistula doi:10.1038/ncpuro1136 Nature Clinical Practice Urology 5, 352 (2008) Nature Clinical Practice Urology 5 7 Research Highlights 352 352 DNA hypomethylation increases the risk of bladder cancer http://dx.doi.org/10.1038/ncpuro1137 DNA hypomethylation increases the risk of bladder cancer

Nature Clinical Practice Urology 5, 352 (2008). doi:10.1038/ncpuro1137

]]> DNA hypomethylation increases the risk of bladder cancer doi:10.1038/ncpuro1137 Nature Clinical Practice Urology 5, 352 (2008) Nature Clinical Practice Urology 5 7 Research Highlights 352 353 Restoration of the penis after accidental amputation during circumcision http://dx.doi.org/10.1038/ncpuro1138 Restoration of the penis after accidental amputation during circumcision

Nature Clinical Practice Urology 5, 353 (2008). doi:10.1038/ncpuro1138

]]> Restoration of the penis after accidental amputation during circumcision doi:10.1038/ncpuro1138 Nature Clinical Practice Urology 5, 353 (2008) Nature Clinical Practice Urology 5 7 Research Highlights 353 353 Factors that influence patients' participation in prostate cancer trials http://dx.doi.org/10.1038/ncpuro1139 Factors that influence patients' participation in prostate cancer trials

Nature Clinical Practice Urology 5, 353 (2008). doi:10.1038/ncpuro1139

]]> Factors that influence patients' participation in prostate cancer trials doi:10.1038/ncpuro1139 Nature Clinical Practice Urology 5, 353 (2008) Nature Clinical Practice Urology 5 7 Research Highlights 353 354 Adding antifibrinolytics to BCG instillations might enhance their antitumor efficacy http://dx.doi.org/10.1038/ncpuro1140 Adding antifibrinolytics to BCG instillations might enhance their antitumor efficacy

Nature Clinical Practice Urology 5, 354 (2008). doi:10.1038/ncpuro1140

]]> Adding antifibrinolytics to BCG instillations might enhance their antitumor efficacy doi:10.1038/ncpuro1140 Nature Clinical Practice Urology 5, 354 (2008) Nature Clinical Practice Urology 5 7 Research Highlights 354 354 Does routine PSA testing decrease prostate cancer mortality? http://dx.doi.org/10.1038/ncpuro1142 Does routine PSA testing decrease prostate cancer mortality?

Nature Clinical Practice Urology 5, 354 (2008). doi:10.1038/ncpuro1142

]]> Does routine PSA testing decrease prostate cancer mortality? doi:10.1038/ncpuro1142 Nature Clinical Practice Urology 5, 354 (2008) Nature Clinical Practice Urology 5 7 Research Highlights 354 354 IMP3 is a promising biomarker in urological cancers http://dx.doi.org/10.1038/ncpuro1141 IMP3 is a promising biomarker in urological cancers

Nature Clinical Practice Urology 5, 355 (2008). doi:10.1038/ncpuro1141

]]> IMP3 is a promising biomarker in urological cancers doi:10.1038/ncpuro1141 Nature Clinical Practice Urology 5, 355 (2008) Nature Clinical Practice Urology 5 7 Research Highlights 355 355 Laparoscopic surgery: a safe option even for vulnerable patients http://dx.doi.org/10.1038/ncpuro1143 Laparoscopic surgery: a safe option even for vulnerable patients

Nature Clinical Practice Urology 5, 355 (2008). doi:10.1038/ncpuro1143

]]> Laparoscopic surgery: a safe option even for vulnerable patients doi:10.1038/ncpuro1143 Nature Clinical Practice Urology 5, 355 (2008) Nature Clinical Practice Urology 5 7 Research Highlights 355 355 Is the Phoenix definition superior to ASTRO for predicting clinical outcomes in prostate cancer? http://dx.doi.org/10.1038/ncpuro1126 Is the Phoenix definition superior to ASTRO for predicting clinical outcomes in prostate cancer?

Nature Clinical Practice Urology 5, 356 (2008). doi:10.1038/ncpuro1126

Author: Andrew J Stephenson

]]> Is the Phoenix definition superior to ASTRO for predicting clinical outcomes in prostate cancer? Andrew J Stephenson doi:10.1038/ncpuro1126 Nature Clinical Practice Urology 5, 356 (2008) 2008-05-20 Nature Clinical Practice Urology 2008-05-20 5 7 Practice Point 356 357 Should holmium laser enucleation be the new gold standard for bladder outlet obstruction caused by BPH? http://dx.doi.org/10.1038/ncpuro1129 Should holmium laser enucleation be the new gold standard for bladder outlet obstruction caused by BPH?

Nature Clinical Practice Urology 5, 358 (2008). doi:10.1038/ncpuro1129

Authors: Gerasimos Alivizatos & Andreas Skolarikos

]]> Should holmium laser enucleation be the new gold standard for bladder outlet obstruction caused by BPH? Gerasimos Alivizatos Andreas Skolarikos doi:10.1038/ncpuro1129 Nature Clinical Practice Urology 5, 358 (2008) 2008-05-20 Nature Clinical Practice Urology 2008-05-20 5 7 Practice Point 358 359 What is the clinical significance of ipsilateral renal lesions during nephron-sparing surgery? http://dx.doi.org/10.1038/ncpuro1130 What is the clinical significance of ipsilateral renal lesions during nephron-sparing surgery?

Nature Clinical Practice Urology 5, 360 (2008). doi:10.1038/ncpuro1130

Authors: Paul L Crispen & Bradley C Leibovich

]]> What is the clinical significance of ipsilateral renal lesions during nephron-sparing surgery? Paul L Crispen Bradley C Leibovich doi:10.1038/ncpuro1130 Nature Clinical Practice Urology 5, 360 (2008) 2008-05-27 Nature Clinical Practice Urology 2008-05-27 5 7 Practice Point 360 361 Nomogram for predicting survival in men with clinically localized prostate cancer who do not undergo definitive therapy http://dx.doi.org/10.1038/ncpuro1131 Nomogram for predicting survival in men with clinically localized prostate cancer who do not undergo definitive therapy

Nature Clinical Practice Urology 5, 362 (2008). doi:10.1038/ncpuro1131

Author: Laurence Klotz

]]> Nomogram for predicting survival in men with clinically localized prostate cancer who do not undergo definitive therapy Laurence Klotz doi:10.1038/ncpuro1131 Nature Clinical Practice Urology 5, 362 (2008) 2008-05-27 Nature Clinical Practice Urology 2008-05-27 5 7 Practice Point 362 363 Is Mohs micrographic surgery a safe and effective treatment option in patients with penile carcinoma? http://dx.doi.org/10.1038/ncpuro1132 Is Mohs micrographic surgery a safe and effective treatment option in patients with penile carcinoma?

Nature Clinical Practice Urology 5, 364 (2008). doi:10.1038/ncpuro1132

Authors: Alberto R Casabé & Esteban N Casabé

]]> Is Mohs micrographic surgery a safe and effective treatment option in patients with penile carcinoma? Alberto R Casabé Esteban N Casabé doi:10.1038/ncpuro1132 Nature Clinical Practice Urology 5, 364 (2008) 2008-06-03 Nature Clinical Practice Urology 2008-06-03 5 7 Practice Point 364 365 Do we need more nomograms for predicting outcomes in patients with prostate cancer? http://dx.doi.org/10.1038/ncpuro1128 In this Viewpoint article by Professor Kattan, the author discusses methods for predicting outcomes in patients with prostate cancer, the predictive accuracy of these methods, and why, despite the large number of nomograms already developed, further nomograms are still needed for predicting outcomes in patients with prostate cancer. Do we need more nomograms for predicting outcomes in patients with prostate cancer?

Nature Clinical Practice Urology 5, 366 (2008). doi:10.1038/ncpuro1128

Author: Michael W Kattan

]]> Do we need more nomograms for predicting outcomes in patients with prostate cancer? Michael W Kattan doi:10.1038/ncpuro1128 Nature Clinical Practice Urology 5, 366 (2008) 2008-05-27 Nature Clinical Practice Urology 2008-05-27 5 7 Viewpoint 366 367 Bladder-sparing therapy for muscle-infiltrating bladder cancer http://dx.doi.org/10.1038/ncpuro1145 Radical cystectomy is the preferred treatment for nonmetastatic muscle-infiltrating bladder cancer, but several researchers have proposed the use of bladder-sparing approaches. In this Review, Pansadoro and Emiliozzi discuss a variety of possible bladder-sparing approaches and the evidence supporting their use. Bladder-sparing therapy for muscle-infiltrating bladder cancer

Nature Clinical Practice Urology 5, 368 (2008). doi:10.1038/ncpuro1145

Authors: Vito Pansadoro & Paolo Emiliozzi

]]> Bladder-sparing therapy for muscle-infiltrating bladder cancer Vito Pansadoro Paolo Emiliozzi doi:10.1038/ncpuro1145 Nature Clinical Practice Urology 5, 368 (2008) 2008-06-17 Nature Clinical Practice Urology 2008-06-17 5 7 Review 368 375 Statins and prostate cancer prevention: where we are now, and future directions http://dx.doi.org/10.1038/ncpuro1146 Many experimental studies have reported that statins, cholesterol-lowering drugs, inhibit the growth of prostate cancer cells. In this Review, Murtola and colleagues look at the current evidence on the use of statins in the prevention of prostate cancer. Statins and prostate cancer prevention: where we are now, and future directions

Nature Clinical Practice Urology 5, 376 (2008). doi:10.1038/ncpuro1146

Authors: Teemu J Murtola, Tapio Visakorpi, Jorma Lahtela, Heimo Syvälä & Teuvo LJ Tammela

]]> Statins and prostate cancer prevention: where we are now, and future directions Teemu J Murtola Tapio Visakorpi Jorma Lahtela Heimo Syvälä Teuvo LJ Tammela doi:10.1038/ncpuro1146 Nature Clinical Practice Urology 5, 376 (2008) 2008-06-10 Nature Clinical Practice Urology 2008-06-10 5 7 Review 376 387 Testosterone deficiency: a common, unrecognized syndrome http://dx.doi.org/10.1038/ncpuro1167 The signs and symptoms of testosterone deficiency can be nonspecific, and can vary according to patient age and the presence of comorbid illnesses, thereby making diagnosis of the disorder difficult. In this Review, Tostain and Blanc highlight the problems and solutions in diagnosing testosterone deficiency by looking at the signs and symptoms, diagnostic tests, and epidemiology of the disorder. Testosterone deficiency: a common, unrecognized syndrome

Nature Clinical Practice Urology 5, 388 (2008). doi:10.1038/ncpuro1167

Authors: Jacques L Tostain & François Blanc

]]> Testosterone deficiency: a common, unrecognized syndrome Jacques L Tostain François Blanc doi:10.1038/ncpuro1167 Nature Clinical Practice Urology 5, 388 (2008) Nature Clinical Practice Urology 5 7 Review 388 396 A case of synchronous bilateral testicular seminoma http://dx.doi.org/10.1038/ncpuro1133 The optimum management of patients with low-stage seminoma remains a matter of debate. Here, Resnick et al. detail the case of a 51-year-old man who was diagnosed with bilateral stage I testicular seminoma. The authors discuss the management of bilateral disease, addressing the implications of surgical castration and the possibility of testis-sparing approaches to treatment. A case of synchronous bilateral testicular seminoma

Nature Clinical Practice Urology 5, 397 (2008). doi:10.1038/ncpuro1133

Authors: Matthew J Resnick, Daniel Canter, Benjamin M Brucker, Alexander Kutikov, Thomas J Guzzo & Alan J Wein

]]> A case of synchronous bilateral testicular seminoma Matthew J Resnick Daniel Canter Benjamin M Brucker Alexander Kutikov Thomas J Guzzo Alan J Wein doi:10.1038/ncpuro1133 Nature Clinical Practice Urology 5, 397 (2008) 2008-06-03 Nature Clinical Practice Urology 2008-06-03 5 7 Case Study 397 401 A case of relapsing secondary bladder adenocarcinoma after right colonic cancer http://dx.doi.org/10.1038/ncpuro1155 Distinguishing primary bladder adenocarcinoma from metastatic colorectal cancer represents a diagnostic challenge; however, a correct diagnosis can prevent the patient from receiving inappropriate treatment. Here, Izzo et al. use the case of a 71-year-old woman to highlight important issues in the diagnosis of these bladder neoplasms, with particular focus on the role of immunohistochemistry. A case of relapsing secondary bladder adenocarcinoma after right colonic cancer

Nature Clinical Practice Urology 5, 403 (2008). doi:10.1038/ncpuro1155

Authors: Luciano Izzo, Dario Pietrasanta, Paolo Izzo, Maria Caputo, Pierfrancesco Di Cello, Paolo Meloni & Antonio Bolognese

]]> A case of relapsing secondary bladder adenocarcinoma after right colonic cancer Luciano Izzo Dario Pietrasanta Paolo Izzo Maria Caputo Pierfrancesco Di Cello Paolo Meloni Antonio Bolognese doi:10.1038/ncpuro1155 Nature Clinical Practice Urology 5, 403 (2008) Nature Clinical Practice Urology 5 7 Case Study 403 407