Review

Nature Clinical Practice Rheumatology (2007) 3, 635-643
doi:10.1038/ncprheum0647  
Received 11 May 2007 | Accepted 20 August 2007

Mechanisms of Disease: angiogenesis in inflammatory diseases

Zoltán Szekanecz* and Alisa E Koch

Correspondence *Third Department of Medicine, Rheumatology Division, University of Debrecen Medical Center, 22 Móricz Zs Street, Debrecen, H-4012, Hungary

Email
 szekanecz@iiibel.dote.hu

Angiogenesis might have a key role in the pathogenesis of inflammatory disorders such as rheumatoid arthritis. The basic mechanisms, mediators and inhibitors of inflammation-associated angiogenesis are outlined in this Review, and the possible clinical application of therapeutics that target angiogenesis are discussed.

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