Does daily calcium supplementation reduce the risk of clinical fractures in elderly women?
Robert P Heaney
Correspondence Creighton University Medical Center, 601 North 30th Street, Suite 4841, Omaha, NE 68131, USA
Email rheaney@creighton.edu
This article has no abstract so we have provided the first paragraph of the full text.
The hypothesis that adequate calcium intake reduces fracture risk has been tested in several studies and has been amply supported. This article by Prince and colleagues illustrates the practical difficulty of ensuring compliance with a nutritional regimen that produces no patient-perceptible benefits. More than 40% of the cohort in this study failed to take 80% of the prescribed supplement doses. These noncompliant patients accounted for 60% of the fractures. The authors conclude that supplementation with calcium is ineffective as a public-health intervention.
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